According to the most recent statistics, cerebrovascular disease is the third leading cause of death in the United States, ranking behind heart attack and all forms of cancer. One form of cerebrovascular disease is the cerebral aneuiysm, which manifests itself as a dilatation, or pouching, of the arterial wall. The dilatation develops at a diseased site along the wall into a distended sac of stressed arterial tissue. Fully developed cerebral aneurysms are typically from 5 to 10 millimeters in diameter. Aneurysms can and do occur at any point within the cardiac and peripheral vasculaturc. However, cerebral aneurysms tend to assume a simple spherical form that makes them well suited to a biophysical analysis. They also pose the greatest risks to the patient. Left untreated, an aneurysm continues to expand until it raptures, causing hemorrhage, severe neurological complications and possibly death. It is for these reasons that this article concentrates on cerebral aneurysms. Many aspects of the treatment given here will be applicable to other types of aneurysms.

1.
1993 Heart and Stroke Facts, Am. Heart Assoc., Dallas (1993).
2.
L. N.
Sekhar
,
R. C.
Heros
,
Neurosurgery
8
,
248
(
1981
).
3.
C. F.
Gonzalez
,
Y. I.
Cho
,
H. V.
Ortega
,
J.
Moret
,
Am. J. Neurol. Res.
13
,
181
(
1992
).
K.
Perktold
,
T.
Kenner
,
D.
Hilbert
,
B.
Spork
,
H.
Florian
,
Basic Res. Cardiol.
83
,
24
(
1988
).
4.
G. M.
Austin
,
W.
Schievink
,
R.
Williams
,
Neurosurgery
24
,
722
(
1989
).
H. J.
Steiger
,
A.
Poll
,
D.
Liepsch
,
H.‐J.
Reulen
,
Heart Vessels
3
,
55
(
1987
).
T.
Hashimoto
,
Neurol. Res.
6
,
22
(
1984
).
M. R.
Roach
,
S.
Scott
,
G. G.
Ferguson
,
Stroke
3
,
255
(
1972
).
5.
T. F.
Massoud
,
C.
Ji
,
G.
Guglielmi
,
F.
Viñuela
,
J.
Robert
,
Am. J. Neurol. Res.
15
,
938
(
1994
).
N.
Hashimoto
,
C.
Kim
,
H.
Kikuchi
,
M.
Kojima
,
Y.
Kang
,
F.
Hazama
,
J. Neurosurg.
67
,
903
(
1987
).
6.
G. J.
Hademenos
,
T.
Massoud
,
D. J.
Valentino
,
G.
Duckwiler
,
F.
Vinuela
,
Neurol. Res.
16
,
376
(
1994
).
N.
Brown
,
Stroke
22
,
619
(
1991
).
P. B.
Canham
,
G. G.
Ferguson
,
J. Neurosurg.
17
,
291
(
1985
).
7.
G. G.
Ferguson
,
J. Neurosurg.
37
,
666
(
1972
).
8.
D. J. Patel, R. N. Vaishnav, Basic Hemodynamics and Its Role in Disease Processes, University Park P., Baltimore (1980), ch. 2.
9.
W. R. Milnor, Hemodynamics, 2nd ed., Williams and Wilkins, Baltimore (1989), ch. 3.
10.
D. R.
Boughner
,
M. R.
Roach
,
Circulation Res.
29
,
136
(
1971
).
11.
G. G.
Ferguson
,
J. Neurosurg.
33
,
485
(
1970
).
12.
W. E.
Stehbens
,
Med. J. Aust.
2
,
8
(
1962
).
13.
G.
Neil‐Dwyer
,
J. R.
Bartlett
,
A. C.
Nicholls
,
P.
Narcisi
,
F. M.
Pope
,
J. Neurosurg.
59
,
16
(
1983
).
14.
R. V. Southwell, An Introduction to the Theory of Elasticity for Engineers and Physicists, Oxford U.P., London (1936), p. 385.
15.
W. E. Stehbens, Hemodynamics and the Blood Vessel Wall, Charles C. Thomas, Springfield, III. (1979), pp. 476–77.
16.
E. J.‐N.
Hung
,
M. R.
Botwin
,
J. Biomech.
8
,
385
(
1975
).
17.
U. Dinnar, Cardiovascular Fluid Dynamics, CRC P., Boca Raton, Fla. (1981), pp. 90–91.
18.
E. F. Binet, E. J. C. Angtuaco, in Neurosurgery, vol. II, R. H. Wilkins, S. S. Rengachary, eds., McGraw‐Hill, New York (1985), p. 1341.
19.
D. J. Valentino, V. Bhushan, R. Kiss, M. Harreld, R. Lufkin, F. Vinuela, D. Gibson, in Medical Imaging 1994: Image Capture, Formatting, and Display, Proc. SPIE 2164, Y. Kim, ed., SPIE, Bellingham, Wash. (1994), p. 393.
20.
G. K.
Geremia
et al.,
Am. J. Neurol. Res.
11
,
659
(
1990
).
E. S.
Kwan
,
C. B.
Heilman
,
P. A.
Roth
,
Am. J. Neurol. Res.
14
,
323
(
1993
).
V. B.
Graves
et al.,
Am. J. Neurol. Res.
11
,
249
(
1990
);
V. B.
Graves
,
13
,
189
(
1992
).
21.
J. R.
Moringlane
et al.,
Acta Neurochir. (Suppl.)
43
,
193
(
1968
).
T.
Suga
et al.,
Neurol. Surg.
20
,
865
(
1992
).
A. S.
Genest
,
J. Neurosurg.
22
,
136
(
1965
).
22.
G.
Mairaetal
et al.
J. Microsurg.
1
,
137
(
1979
).
G. V.
O’Reilly
et al.,
Radiology
171
,
471
(
1989
).
23.
P. S.
Slosberg
,
Mount Sinai J. Med. N. Y.
40
,
82
(
1973
).
W. Grand, in Clinical Management of Intracranial Aneurysms L. N. Hopkins, D. M. Long, eds., Raven, New York (1982), p. 29.
24.
G.
Guglielmi
,
F.
Vinuela
,
J.
Dion
,
G.
Duckwiler
,
J. Neurosurg
75
,
8
(
1991
).
25.
H. W. M. ter
Berg
,
D. W. J.
Dippel
,
M.
Limburg
,
W. I.
Schievink
,
J. van
Gijn
,
Stroke
23
,
1024
(
1992
).
This content is only available via PDF.
You do not currently have access to this content.