What current and emerging problems of national significance can be identified through scientific research? What are the opportunities for, and constraints on, the use of new and existing scientific and technological capabilities toward a resolution of these problems?

See, for example, E. P. Wigner, Communications on Pure and Applied Mathematics, 13 (no. 1), February 1960.
V. Weisskopf in Science, Invention and Social Change (A Rosenfeld, ed.), General Electric Co., Schenectady, N.Y. (1978); page 17.
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