In this clinical study, we proposed to observe the efficacy of the treatment of squamous cell carcinoma of the tongue (SCCT) by carbon dioxide (CO2) laser surgery. Twelve patients with SCCT were treated with excisional surgery using the CO2 laser with a spot size of 0.8 mm, 10 W, power density of 2.5 W/cm2 in continuous mode, and under constant vacuum removal of the plume. The post surgical clinical evaluations were done every day until the sutures were removed and then every 7 days up to 1 month postoperatively. Subjects were re-examined quarterly until the fifth year post surgery. After 5 yr of follow-up for all subjects, there was no recurrence of the SCCT at the involved sites. The functional and aesthetic results observed were excellent. It is concluded that CO2 laser ablation of SCCT is an extremely useful surgical technique that can provide a clean field and is capable of providing surgical results consistent with accepted principles of oncological surgery.

1.
W.
Garavello
,
R.
Spreafico
, and
R. M.
Gaini
, “
Oral tongue cancer in young patients: A matched analysis
,”
Oral Oncol.
43
,
894
897
(
2007
).
2.
J. P.
O’Neill
,
J. P.
Hughes
,
K. P.
Manning
, and
J. E.
Fenton
, “
Controversies in the management of tongue base cancer
,”
Ir. J. Med. Sci.
178
,
1
5
(
2009
).
3.
S.
Prince
and
B. M. W.
Bailey
, “
Squamous carcinoma of the tongue: Review
,”
Br. J. Oral Maxillofac Surg.
37
,
164
174
(
1999
).
4.
A.
Argiris
,
M. V.
Karamouzis
,
D.
Raben
, and
R. L.
Ferris
, “
Head and neck cancer
,”
Lancet
371
,
1695
1709
(
2008
).
5.
U.
Duvvuri
and
J. N.
Myers
, “
Contemporary management of oropharyngeal cancer
,”
Curr. Probl Surg.
46
,
119
184
(
2009
).
6.
J. P.
Shah
and
Z.
Gil
, “
Current concepts in management of oral cancer—Surgery
,”
Oral Oncol.
45
,
394
401
(
2009
).
7.
A.
Burkhart
and
R.
Maerker
,
Oral Cancers
(
Carl Hanser Verlag
,
München
,
1981
).
8.
O.
Pradier
,
H.
Christiansen
,
H.
Schmidberger
,
A.
Martin
,
M. C.
Jäckel
,
W.
Steiner
,
P.
Ambrosch
,
E.
Kahler
, and
V. F.
Hess
, “
Adjuvant radiotherapy after transoral laser microsurgery for advanced squamous carcinoma of the head and neck
,”
Int. J. Radiat. Oncol., Biol., Phys.
63
,
1368
1377
(
2005
).
9.
C.
Taneja
,
H.
Allen
,
R. J.
Koness
,
K.
Radie–Keane
, and
H. J.
Wanebo
, “
Changing patterns of failure of head and neck cancer
,”
Arch. Otolaryngol. Head Neck Surg.
128
,
324
327
(
2002
).
10.
J. N.
Myers
,
J. S.
Greenberg
,
V.
Mo
,
D.
Roberts
, “
Extracapsular spread. A significant predictor of treatment failure in patients with squamous cell carcinoma of the tongue
,”
Cancer
92
,
3030
3036
(
2001
).
11.
C. E.
Schmalbach
and
F. R.
Miller
, “
Occult primary head and neck carcinoma
,”
Curr. Oncol. Rep.
9
,
139
146
(
2007
).
12.
A. P. W.
Yuen
, “
Cancer of the tongue
,”
Oper. Tech. Otolaryngol.
15
,
234
(
2004
).
13.
H.
Keski-Säntti
,
T.
Atula
,
J.
Törnwall
,
P.
Koivunen
, and
A.
Mäkitie
, “
Elective neck treatment versus observation in patients with T1/T2 N0 squamous cell carcinoma of oral tongue
,”
Oral Oncol.
42
,
96
101
(
2006
).
14.
C.
Scully
and
J.
Bagan
, “
Oral squamous cell carcinoma overview
,”
Oral Oncol.
45
,
301
308
(
2009
).
15.
M. N.
Lango
, “
Multimodal treatment for head and neck cancer
,”
Surg. Clin. North Am.
89
,
43
52
(
2009
).
16.
R. A.
Strauss
and
S. D.
Fallon
, “
Lasers in contemporary oral and maxillofacial surgery
,”
Dent. Clin. North Am.
48
,
861
888
(
2004
).
17.
J.
Ilgner
and
M.
Westhofen
, “
Laser interventions in otorhinolaryngology—Current techniques and future developments
,”
Med. Laser Appl.
25
,
27
(
2010
).
18.
H.
Deppe
and
H. H.
Horch
, “
Current status of laser applications in oral and cranio-maxillofacial surgery
,”
Med. Laser Appl.
22
,
39
42
(
2007
).
19.
L.
Clayman
and
P.
Kuo
,
Lasers in Maxillofacial Surgery and Dentistry
(
Thieme
,
New York
,
1997
).
20.
T. J.
Paes-Junior
and
W.
Niccoli-Filho
, “
Clinical comparison between conventional suture and vaporization with carbon dioxide laser in rat’s skin
,”
J. Clin. Laser Med. Surg.
6
,
319
324
(
2001
).
21.
S.
Barak
,
I.
Kaplan
, and
I.
Rosenblum
, “
The use of the CO2 laser in oral and maxillofacial surgery
,”
J. Clin. Laser Med. Surg.
10
,
69
70
(
1990
).
22.
G. C.
Riggle
,
R. C.
Hoyle
, and
S. S.
Ketcham
, “
Laser effects on normal and tumour tissue
,” in
Laser Applications in Medicine and Biology
(
Plenum
,
New York
,
1971
), pp.
36
65
.
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