Solid state tunable lasers offer the unique potential of continuous tunability with one laser over the spectral region of photochemistry, 1000 - 100 nm. A laser with this unbroken tuning range, of sufficient accuracy and demand of time pulse structure, would allow more specific analysis of the nature of chromophores and their role in photobiology resulting from UV radiation. We are particularly attracted to a laser of this capabiliity to place in the hands of profesional investigators of chromosomology and the related RNA and DNA.

The use of state of the art solid state tunable lasers, (Nd:Yag, Argon-ion, etc. with input frequencies ranging from 1600 - 550 nm) and frequency up-conversion with highly efficient non-linear crystals in addition provide the following advantages:

  • Relatively low cost.

  • Fast beam steering (wavelength varying).

  • Frequency up conversion through harmonic generation to 198 nm.

  • Simultaneous multi-color output (continuous).

Other specific features for newly developed crystals are: (1) high damage threshold, (2) very high non-linear coefficients, (3) wide temperature stability, and (4) excellent optical qualities and phase matching angles.

The laser currently being tested has been designed to be highly reliable and user friendly. The entire system is computer controlled and menue driven with associated graphics. Time pulse structures of both picoseconds and femtoseconds as well as modified CW outputs are available on demand. The system has further been designed to be mechanically and optically adapted, through the use of various types and sizes of fiber optics, to the end-user equipment of the investigator.

1.
Wang
,
Shih Yi
(
1976
)
Photochemistry and Photobiology of Nucleic Acids
.
Academic Press
,
New York
.
9
29
.
2.
Carroll
,
R. L.
(Sept.
1986
)
The Dye Laser’s Surgical Successes
.
Photonics Spectra.
101
106
.
3.
Moretti
,
M.
(April
1987
)
A Status Report on Lasers in Medicine
.
Laser Focus/Electro-Optics
.
88
97
.
4.
Berns
,
M. W.
et al (July
1981
)
Laser Microsurgery in Cell and Developmental Biology
.
Science
.
213
:
505
513
.
5.
Rampone
,
R.
and
Svelto
O.
(
1985
)
Potential Applications of Free-Electron Lasers in Biomedicine
.
Nuclear Inst, and Methods in Phys. Res.
A239
:
386
389
.
6.
Danly
,
B. G.
,
Temkin
R. J.
and
Bekefi
G.
(Oct.
1987
)
Free-Electron Lasers and their Applications to Biomedicine
.
IEEE Jol. Quant. Elec.
QE-
23
:
1739
1750
.
7.
Holmes
,
L.
(April
1986
)
Tunable Crystals and Diodes in the Infrared
.
Laser Focus/Electro-Optics.
70
76
.
8.
Moulton
,
P. F.
(August
1987
)
Tunable Solid State Lasers Targeted for a Variety of Applications
.
Laser Focus/Electro-Optics
.
56
69
.
9.
Phillips
R. M.
(Oct
1960
)
The Ubitron, A High Powered Traveling-Wave Tube Based on a Periodic Beam Interaction in Unloaded Waveguide
.
IRE Trans, on Electron Devices
. ED-
7
:
231
241
.
10.
DeMaria
,
A. J.
,
Glenn
W. H.
, Jr.
,
Brienza
M. J.
, and
Mack
M. E.
(Jan.
1969
)
Picosecond Laser Pulses
.
Proc. of the IEEE
57
:
2
25
.
11.
Lin
,
J. T.
(
1986
)
Analysis of Frequency Conversion and Applications of New Nonlinear Crystals
.
Proc. International Conf. on Lasers 86
.
12.
Me Mahon
,
J. A.
(Aug.
1986
)
Council Report on Lasers in Medicine and Surgery
.
JAMA
.
256
:
900
909
.
13.
Winburn
,
D. C.
(Apr.
1981
)
Laser Protective Eye Wear: How Safe is it?
Laser Focus/Electro-Optics
.
136
140
.
14.
Oelfke
,
W. C.
(Sept.
1973
)
Heads Up Display System Using Nonparaxial Holographic Lenses
.
Technical Note: NAVTRAEQUIPCEN TN-38
.
This content is only available via PDF.
You do not currently have access to this content.