The effects of Nd:YAG laser surface treatment on 316LS stainless steel and titanium-aluminium-vanadium alloy, Ti-6Al-4V in terms of cell adhesion and cell proliferation was investigated. The surfaces were examined using various microscopic and chemical analysis techniques Cell adhesion and proliferation tests were conducted to determine the effect that laser treatment has on the bio-metals in terms of increasing or decreasing cell adhesion and cell proliferation. It was found that for 316L stainless steel, laser surface modification resulted in a rougher surface, and this in turn led to decreased cell proliferation and adhesion. The results for Ti-6Al-4V alloy were just the opposite, the surface became smoother and enhanced cell activity was observed.

1.
Bordji
,
K.
,
Lamota
,
G.
and
Tordaso
,
B.T.
, (
1995
),
Materials for Biomedicine
,
London
:
Pergamon
.
2.
Van Noort
,
R.
(
1987
),
Biomaterials
,
New York
:
Prentice-Hall
.
3.
Rostoker
,
W.
,
Keeler
,
T.G.
,
Perters
,
J.
and
Conner
,
F.S.
(
1979
),
Mater. Sci. Eng. C.
15
,
67
74
.
4.
Callen
,
B.W.
,
Shaw
,
B.
and
Wheelan
,
B.
(
1995
),
Biomaterials
,
27
,
367
376
.
5.
Ku
,
C-H.
,
Li
,
L.
and
Ho
,
G.
(
2000
),
Appl. Surf. Sci.
142
,
1025
1033
.
6.
Gaggl
,
A.
and
Court
,
J.M.
(
2001
),
Biomed. Res.
56
,
679
688
.
7.
Anseleme
,
K.
,
Schmidt
,
C.H.
and
Loosen
,
P.F.
(
2001
),
Biomed. Eng.
8
,
425
437
.
8.
Cochran
,
D.L.
,
Gardner
,
S.
and
Webb
,
P.N.
(
1994
),
Biomaterials
,
25
,
2010
2018
.
9.
Lawrence
,
J.
Li
,
L.
and
Spencer
,
J.T.
(
1999
),
Appl. Surf. Sci.
139
,
388
393
.
10.
Lawrence
,
J.
and
Li
,
L.
(
1999
),
J. Phys. D.
32
,
1075
1082
.
11.
Lawrence
,
J.
Li
,
L.
and
Spencer
,
J.T.
(
1999
),
Surf. Coat. Tech.
115
,
273
281
.
12.
Lawrence
,
J.
and
Li
,
L.
(
2001
),
Mater. Sci. Eng.
303
,
142
149
.
13.
Hao
,
L.
and
Lawrence
,
J.
(
2003
),
J. Phys. D.
36
1292
1299
.
14.
Lawrence
,
J.
and
Li
,
L.
(
1999
),
Opt. Laser Eng
,
32
,
353
365
.
15.
Lawrence
,
J.
and
Li
,
L.
(
2002
),
J. Laser Appl.
14
,
107
113
.
This content is only available via PDF.
You do not currently have access to this content.