Single Molecule Biophysics

Single-molecule measurements are now almost routinely used to study biological systems and processes. The scope of this special topic emphasizes the physics side of single-molecule observations, highlighting new developments in physical techniques as well as conceptual insights that single-molecule measurements bring to biophysics. This issue also comprises recent advances in theoretical physical models of single-molecule phenomena, interpretation of single-molecule signals, and fundamental areas of statistical mechanics that are related to single-molecule observations. The articles in this collection illustrate the increasing synergy between theory, simulation, and experiment in single-molecule biophysics.

Guest Editors: Dmitrii E. Makarov and Benjamin Schuler