FIG. 12.11 (a) Customized hand-held type US transducer with 2-D curved arrays. (i) Schematic of the hand-held type US transducer. (ii) 3-D image of the abdomen and (iii) whole body of a mouse. (b) Customized stationary US transducer with 2-D curved CMUT arrays. Schematic of the stationary US transducer in the (i) yz plane and (ii) xy plane, respectively. (iii) Representative PA MAP image of a human hand. Reprinted with permission from Deán-Ben, X. L. et al. , Light: Sci. Appl. 6 (4), e16247 (2017a). Copyright 2017 Author(s); Matsumoto, Y. et al. , Sci. Rep. 8 (1), 14930 (2018). Copyright 2018 Author(s). US: ultrasound; HAD: hemispherical detector array; MAP: maximum amplitude projection. More about this image found in (a) Customized hand-held type US transducer with 2-D curved arrays. (i) Sch...

FIG. 12.6 (a) (i) Photograph of a 3-D PA imaging system with a conventional linear array US transducer and motorized stage. (ii) Volume PA image of a phantom. (b) Schematic of signal reception in the elevation direction when using (i) a conventional linear array US transducer and (ii) the conventional linear array US transducer with slit at a focal zone. PA MAP images of mouse abdomen taken by (iii) a conventional 3-D PA imaging system and (iv) slit-enabled 3-D PA imaging system. Reprinted with permission from Wang, Y. et al. , Opt. Lett. 41 (1), 127–130 (2016). Copyright 2016 Optica Publishing Group; Tan, Y. et al. , Opt. Express 25 (7), 8022–8028 (2017). Copyright 2017 Optica Publishing Group. PA: photoacoustic; US: ultrasound; MAP: maximum amplitude projection. More about this image found in (a) (i) Photograph of a 3-D PA imaging system with a conventional linear ar...

FIG. 12.9 (a) (i) Schematic and (ii) photograph of a 1-D concave shaped US transducer. (iii) Representative B-mode PA image of human thyroid. (b) (i) Photograph of a hand-held 1-D curved array US transducer. The transducer integrates a light delivery system. (ii) Simulation result of sensitivity distribution in xy and yz planes. Focusing is mechanically fixed. Reprinted with permission from Buehler, A. et al. , Opt. Lett. 38 (9), 1404–1406 (2013). Copyright 2013 Optica Publishing Group; Dima, A. and Ntziachristos, V. , Photoacoustics 4 (2), 65–69 (2016). Copyright 2016 Author(s). US: ultrasound; PA: photoacoustic. More about this image found in (a) (i) Schematic and (ii) photograph of a 1-D concave shaped US transducer...

FIG. 12.5 2-D PACT imaging system. (a) (i) Photograph of a conventional 1-D linear array US transducer with a light delivery system. (ii) Representative overlaid B-mode and PA/US image of a human lymph node. The PA image shows SLN expressed in pseudo color. (b) (i) Photograph of a conventional 1-D concave shaped US transducer integrated with an illumination system. (ii) Representative co-registered PA/US image of prostate. NVB is indicated by PA signals on the prostate's posterolateral surface. (c) (i) Transvaginal PA/US imaging system using conventional US transducer. (ii) Ex-vivo co-registered PA/US image of benign human ovary. Blood vessels around the cyst can be identified by a PA image shown in red. (iii) Photograph of H&E staining of the ovary. Reprinted with permission from Garcia-Uribe, A. et al. , Sci. Rep. 5 , 15748 (2015). Copyright 2015 Author(s); Salehi, H. S. et al. , Photoacoustics 3 (3), 114–122 (2015). Copyright 2015 Author(s); Ishihara, M. et al. , Photons Plus Ultrasound Imaging and Sensing 2016 (International Society for Optics and Photonics, 2016). Copyright 2016 SPIE; Ishihara, M. et al. , Photons Plus Ultrasound Imaging and Sensing 2017 (International Society for Optics and Photonics, 2017). Copyright 2017 SPIE. PACT: photoacoustic computed tomography; US: ultrasound; NVB: neurovascular bundle; H&E: hematoxylin and eosin. More about this image found in 2-D PACT imaging system. (a) (i) Photograph of a conventional 1-D linear ar...

FIG. 12.7 3-D PA imaging system based on a 2-D matrix-array US transducer. (i) Schematic of the 3-D PA imaging system. PA MAP images of human hair along (ii) the azimuth and (iii) elevation directions. (iv) B-mode PA image of the hair. (v)–(vii) Measured PA amplitudes of the regions indicated by white dashed lines in (i)–(iii). Reprinted with permission from Wang, Y. et al. , J. Biomed. Opt. 17 (6), 061208 (2012). Copyright 2012 SPIE. DAQ: data acquisition; US: ultrasound. More about this image found in 3-D PA imaging system based on a 2-D matrix-array US transducer. (i) Schema...

FIG. 10.6 Examples of endoscopic OCE imaging probes. (a) Integrated ARF OCE imaging probe for cardiac tissue imaging. (i) Photograph of multitransducer ultrasound array (scale bar is 2 mm) and (ii) schematic diagram of the assembled multitransducer ARF OCE imaging probe. Adapted from Karpiouk, A. B. et al., J. Biomed. Opt. 23 , 105006 (2018). Copyright 2018 SPIE. (b) Endoscopic OCE imaging probe for imaging vascular lesions. (i) Overview of acoustic radiation force impulse (ARFI) OCE system setup. C: collimator; L: lens; A: attenuator; M: mirror; G: grating; MS: mechanical stage; RFA: radio frequency amplifier; P: probe; S: sample; FG: function generator. Photographs of (ii) probe design and (iii) probe head including a ring transducer and optical elements. Adapted from Qu, Y. et al., Sci. Rep. 7 , 4731 (2017). Copyright 2017 Author(s), licensed under a Creative Commons Attribution 4.0 License. (c) Anatomical OCE imaging probe for airway imaging. Schematic diagrams of (i) anatomical OCE system with ventilation setup and (ii) the ball-lens structure at the tip of the anatomical OCE imaging probe. Adapted from Bu, R. et al., Opt. Express 27 , 16751–16766 (2019). Copyright 2019 The Optical Society. More about this image found in Examples of endoscopic OCE imaging probes. (a) Integrated ARF OCE imaging p...