... of Pennsylvania , 1996 ). Ozturk , M. , Lee , V. , Zhao , L. , Dai , G. , and Intes , X. , “ Mesoscopic fluorescence molecular tomography of reporter genes in bioprinted thick tissue ,” J. Biomed. Opt.   18 ( 10 ), 100501 ( 2013 ) 10.1117/1.JBO.18.10.100501 . Ozturk , M. S...

...Fluorescence diffuse optical tomography fluorescence molecular tomography forward model inverse problem illumination detection biomarkers pre-clinical research translational imaging mesoscopic fluorescence molecular tomography Introduction Fluorescence imaging has been central...

... centimeters while keeping cellular and tissue level resolution. Photoacoustic tomography can resolve mesoscopic structures at a scale between cells and organs. The imaging system can map 3D micro-circulation networks from the absorption contrast of hemoglobins. Based on this digitized tomographic...

... Yang , F. , Ozturk , M. S. , Zhao , L. , Cong , W. , Wang , G. , and Intes , X. , “ High-resolution mesoscopic fluorescence molecular tomography based on compressive sensing ,” IEEE Trans. Biomed. Eng.   62 ( 1 ), 248 – 255 ( 2015 ). 10.1109/TBME.2014.2347284 Young...

... fluorescence microscopy Fluorescence 0.5–10 µm <1.5 mm Photoacoustic microscopy (PAM) Absorption 0.5–10 µm <1 mm Raman microscopy Raman 0.5–10 µm <0.2 mm Optical coherence tomography (OCT) Scattering 0.5–10 µm <1.5 mm Tomographic imaging Diffuse optical/correlation...

... Yang , F. , Ozturk , M. S. , Zhao , L. , Cong , W. , Wang , G. , and Intes , X. , “ High-resolution mesoscopic fluorescence molecular tomography based on compressive sensing ,” IEEE Trans. Biomed. Eng.   62 ( 1 ), 248 – 255 ( 2015 ). 10.1109/TBME.2014.2347284 Young...

... by Raman microscopy: Using AFM for decoupling molecular concentration and cell topography ,” Faraday Discuss.   187 , 199 – 212 ( 2016 ). 10.1039/c5fd00172b Corden , C. J. , Shipp , D. W. , Matousek , P. , and Notingher , I. , “ Fast Raman spectral mapping of highly fluorescing...

... International Conference on Computational Photography (ICCP) ( IEEE , 2016 ). Barson , D. , Hamodi , A. S. , Shen , X. , Lur , G. , Constable , R. T. , Cardin , J. A.   , “ Simultaneous mesoscopic and two-photon imaging of neuronal activity in cortical circuits ,” Nat. Methods...

... competition with fluorescence and other natural radiative processes. Stimulated Raman scattering (SRS) is another non-linear scattering process. SRS also employs pump and Stokes beams to drive molecular transitions into an excited vibrational state, however, this transition is stimulated Stokes Raman...

... imaging ( Wang et al., 2016 ; and Wang and Xia, 2019 ). For example, the combination of one-photon fluorescence microscopy and photoacoustic computed tomography can perform volumetric imaging of zebrafish ( Deán-Ben et al., 2016 ). Similarly, the combination of one-photon fluorescence...