... sensitive, faster, cheaper, and easy-to-use method for detection. Cantilever-based sensors have been extensively used in the biosensing domain. It has been reported cantilever-based sensors can detect multiple biomarkers ( Bietsch et al., 2004 ; and Basu et al., 2020a ). Diagnostic...

...Shah, A. D., Paudyal, R., Hatzoglou, V., and Shukla-Dave, A. (2021), “Quantitative magnetic resonance imaging biomarkers for head and neck and thyroid cancers,” in Quantitative Imaging in Medicine: Applications and Clinical Translation, edited by R. J. Nordstrom (AIP Publishing, Melville...

... ). It is widely anticipated that continued research and development into biomarkers and feedback algorithms will further improve the efficacy of DBS therapies in the coming decades. FIG. 1.5 Schematic showing key components of a standard deep brain stimulation system. The glucose biosensor Leland C Clark...

... to the transducer, is due to the chance to detect a plethora of clinically relevant biomarkers, present in different body fluids, such as blood, saliva, urine, and tears. For instance, enzymatic biosensors, involving enzymes as biorecognition elements, are particularly suitable for the detection of metabolites...

.... , “ Organic field-effect transistor platform for label-free, single-molecule detection of genomic biomarkers ,” ACS Sens.   5 ( 6 ), 1822 – 1830 ( 2020b ). 10.1021/acssensors.0c00694 Macchia , E. , Romele , P. , Manoli , K. , Ghittorelli , M. , Magliulo , M. , Kovács-Vajna , Z...

... requires pharmacologic agents to undergo first-pass metabolism and cross the blood–brain barrier before being able to modulate the central nervous system. Diagnostics and biomarkers Investigating biological indicators in the nervous system helps us to characterize neurological disorders. While non...

... ( Cacopardo et al., 2019 ). A fully integrated multi-sensor modular platform of OoC organoids comprising physical and electrochemical sensors (e.g., pH, O₂, temperature, and soluble protein biomarker sensing) as well as miniature microscopes was developed and validated for drug-induced...

.... , Hoffman , A. S. , and Lai , J. J. , “ Stimuli-responsive reagent system for enabling microfluidic immunoassays with biomarker purification and enrichment ,” Bioconjug. Chem.   26 ( 1 ), 29 – 38 ( 2015 ). 10.1021/bc500522k Jiang , Y. , Hu , C. , Cheng , H. , Li , C. , Xu...

... together during the elevation of the temperature above the LCST of PNIPAAm. Reproduced with permission from Hoffman, Adv. Drug Deliv. Rev. 65 (1), 10–16 ( 2013 ). Copyright 2013 Elsevier Science Ltd. FIG. 7.4 Captured biomarker by antibodies bound to PNIPAAm-coated gold nanoparticles (NPs) in blood...

... systems exposure event networks for exposure science research ,” Biomarkers   16 ( 2 ), 99 – 105 ( 2011 ). 10.3109/1354750X.2010.541565 Starr , J. , Gemma , A. , Graham , S. , and Stout , D. , “ A test house study of pesticides and pesticide degradation products following...

... systems exposure event networks for exposure science research ,” Biomarkers   16 ( 2 ), 99 – 105 ( 2011 ). 10.3109/1354750X.2010.541565 Starr , J. , Gemma , A. , Graham , S. , and Stout , D. , “ A test house study of pesticides and pesticide degradation products following...

.... Res.   203 , 111871 ( 2022 ). 10.1016/j.envres.2021.111871 Wild , C. P. , “ Complementing the genome with an ‘exposome’: The outstanding challenge of environmental exposure measurement in molecular epidemiology ,” Cancer Epidemiol. Biomark. Prev.   14 ( 8 ), 1847 – 1850 ( 2005...

... , A. , Vachani , A. , and Blair , I. A. , “ 8-Oxo-2′-deoxyguanosine as a biomarker of tobacco-smoking-induced oxidative stress ,” Free Radic. Biol. Med.   53 ( 3 ), 610 – 617 ( 2012 ). 10.1016/j.freeradbiomed.2012.04.006 Meyer , D. E. , Bailin , S. C. , Vallero , D. , Egeghy , P...

... et al., 2008 ). Conversely, reverse dosimetry or dose reconstruction models are designed to estimate the total dose responsible for the measured biomarker, i.e., the concentration of chemical compounds found in urine, blood, or tissue ( U.S. Environmental Protection Agency, 2019 ). Endogenous...

.... Biomark. Prev.   14 ( 8 ), 1847 – 1850 ( 2005 ). 10.1158/1055-9965.EPI-05-0456 Williams , A. J.   , “ The CompTox chemistry dashboard: A community data resource for environmental chemistry ,” J. Cheminform.   9 ( 1 ), 61 ( 2017 ). 10.1186/s13321-017-0247-6 Wolfe , K. , Pope...

... epidemiology ,” Cancer Epidemiol. Biomark. Prev.   14 ( 8 ), 1847 – 1850 ( 2005 ). 10.1158/1055-9965.EPI-05-0456 Williams , A. J.   , “ The CompTox chemistry dashboard: A community data resource for environmental chemistry ,” J. Cheminform.   9 ( 1 ), 61 ( 2017 ). 10.1186/s13321-017-0247-6...