Paracetamol tablet was analyzed by x-ray photoelectron spectroscopy (XPS). Sample was fixed to a stainless-steel sample holder with a copper double-sided adhesive tape. Survey spectra, C 1s, O 1s, N 1s, Si 2p, Mg 2s, Mg KLL, and Mg 1s core levels spectra were acquired. Results showed the presence of carbon, oxygen, and nitrogen, elements that constitute the chemical structure of paracetamol; however, these can also be part of the excipients. In addition, silicon and magnesium were detected, which are related to excipients.
REFERENCES
1.
World Health Organization
, World Health Organization model list of essential medicines 21st list 2019
(World Health Organization
, Geneva
, 2019
).2.
Z. N.
Ennis
, D.
Dideriksen
, H. B.
Vaegter
, G.
Handberg
, and A.
Pottegard
, Basic Clin. Pharmacol. Toxicol.
118
, 184
(2016
). 3.
J.
Foster
, A.
Mauger
, K.
Thomasson
, S.
White
, and L.
Taylor
, Front. Pharmacol.
7
, 1
(2016
). 4.
T.
Wong
, A. S.
Stang
, H.
Ganshorn
, L.
Harting
, I. K.
Maconochie
, A. M.
Thomsen
, and D. W.
Jhonson
, Evidence-Based Child Health Cochrane Rev. J.
9
, 675
(2014
). 5.
AHFS Drug Information 2013
(American Society of Health-System Pharmacists
, USA
, 2013
).6.
P. G.
Rouxhet
and M. J.
Genet
, Surf. Interface Anal.
43
, 1453
(2011
). 2023 Published under an exclusive license by the AVS.
2023
Author(s)
You do not currently have access to this content.
