This study investigated CuO and ZnO nanoparticles and CuO/ZnO nanocomposites in a friendly environment with a low-cost and renewable biosynthesis method. This approach involved using Boehmeria nivea leaf extract to facilitate the growth and formation of nanocomposites with performance-enhancing phytochemicals released during the co-precipitation process. All nanoparticles/nanocomposites explored the microstructure, morphology, and point defects using FTIR, XRD, SEM, and PL characterization techniques. The synthesized CuO and ZnO nanoparticles and CuO/ZnO nanocomposites were evaluated for their antibacterial ability against both bacteria Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). Combining different copper and zinc salt ratios creates different arrangements and morphologies between the CuO sheets and the spherical ZnO nanoparticles. The heterojunction of CuO/ZnO samples enhances the antibacterial effects of nanocomposites compared to pure CuO and ZnO nanoparticles. The maximum antibacterial performance was achieved at 250 ppm against E. coli and 500 ppm against S. aureus in CuO50/ZnO50 nanocomposites. This study shows that a green synthesis of CuO/ZnO nanocomposites promises great potential for environmental treatment and biochemical applications.
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November 2022
Research Article|
November 07 2024
Enhancement of antibacterial activities of green synthesized-CuO/ZnO nanocomposites using Boehmeria nivea leaf extract
Truong Phi Le
;
Truong Phi Le
(Funding acquisition, Investigation, Methodology, Writing – original draft)
1
Faculty of Biology and Biotechnology, University of Science
, Ho Chi Minh City, 700000, Vietnam
2
Vietnam National University
, Ho Chi Minh City, 700000, Vietnam
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Ngoc Hong Nguyen
;
Ngoc Hong Nguyen
(Methodology, Writing – original draft)
1
Faculty of Biology and Biotechnology, University of Science
, Ho Chi Minh City, 700000, Vietnam
3
Faculty of Materials Science and Technology, University of Science
, Ho Chi Minh City 700000, Vietnam
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Vien Ky Le
;
Vien Ky Le
(Data curation)
1
Faculty of Biology and Biotechnology, University of Science
, Ho Chi Minh City, 700000, Vietnam
2
Vietnam National University
, Ho Chi Minh City, 700000, Vietnam
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Phu-Quan Pham
;
Phu-Quan Pham
(Formal analysis)
1
Faculty of Biology and Biotechnology, University of Science
, Ho Chi Minh City, 700000, Vietnam
3
Faculty of Materials Science and Technology, University of Science
, Ho Chi Minh City 700000, Vietnam
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Trung Bao Ngoc Duong
;
Trung Bao Ngoc Duong
(Data curation)
1
Faculty of Biology and Biotechnology, University of Science
, Ho Chi Minh City, 700000, Vietnam
2
Vietnam National University
, Ho Chi Minh City, 700000, Vietnam
3
Faculty of Materials Science and Technology, University of Science
, Ho Chi Minh City 700000, Vietnam
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Quy Ngoc Nguyen Le
;
Quy Ngoc Nguyen Le
(Data curation)
1
Faculty of Biology and Biotechnology, University of Science
, Ho Chi Minh City, 700000, Vietnam
3
Faculty of Materials Science and Technology, University of Science
, Ho Chi Minh City 700000, Vietnam
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Tien Cam Thi Nguyen
;
Tien Cam Thi Nguyen
(Data curation)
1
Faculty of Biology and Biotechnology, University of Science
, Ho Chi Minh City, 700000, Vietnam
2
Vietnam National University
, Ho Chi Minh City, 700000, Vietnam
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Thuy Dieu Thi Ung
;
Thuy Dieu Thi Ung
(Data curation)
4
Institute of Materials Science, Vietnam Academy of Science and Technology
, Hanoi 700000, Vietnam
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Anh Tuan Thanh Pham
;
Anh Tuan Thanh Pham
(Formal analysis)
5
Laboratory of Advanced Materials, University of Science
, Ho Chi Minh City 700000, Vietnam
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Linh Ho Thuy Nguyen
;
Linh Ho Thuy Nguyen
(Formal analysis)
1
Faculty of Biology and Biotechnology, University of Science
, Ho Chi Minh City, 700000, Vietnam
6
Center for Innovative Materials and Architectures (INOMAR)
, Ho Chi Minh City 700000, Vietnam
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Ngoc Xuan Dat Mai
;
Ngoc Xuan Dat Mai
(Validation)
1
Faculty of Biology and Biotechnology, University of Science
, Ho Chi Minh City, 700000, Vietnam
6
Center for Innovative Materials and Architectures (INOMAR)
, Ho Chi Minh City 700000, Vietnam
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Lan Thi My Nguyen
;
Lan Thi My Nguyen
a)
(Conceptualization, Supervision)
1
Faculty of Biology and Biotechnology, University of Science
, Ho Chi Minh City, 700000, Vietnam
2
Vietnam National University
, Ho Chi Minh City, 700000, Vietnam
a)Authors to whom correspondence should be addressed: ntmlan@hcmus.edu.vn and phamkngoc@hcmus.edu.vn
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Ngoc Kim Pham
Ngoc Kim Pham
a)
(Conceptualization, Funding acquisition, Supervision, Writing – review & editing)
1
Faculty of Biology and Biotechnology, University of Science
, Ho Chi Minh City, 700000, Vietnam
3
Faculty of Materials Science and Technology, University of Science
, Ho Chi Minh City 700000, Vietnam
a)Authors to whom correspondence should be addressed: ntmlan@hcmus.edu.vn and phamkngoc@hcmus.edu.vn
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a)Authors to whom correspondence should be addressed: ntmlan@hcmus.edu.vn and phamkngoc@hcmus.edu.vn
Biointerphases 19, 061001 (2022)
Article history
Received:
June 25 2024
Accepted:
October 09 2024
Citation
Truong Phi Le, Ngoc Hong Nguyen, Vien Ky Le, Phu-Quan Pham, Trung Bao Ngoc Duong, Quy Ngoc Nguyen Le, Tien Cam Thi Nguyen, Thuy Dieu Thi Ung, Anh Tuan Thanh Pham, Linh Ho Thuy Nguyen, Ngoc Xuan Dat Mai, Lan Thi My Nguyen, Ngoc Kim Pham; Enhancement of antibacterial activities of green synthesized-CuO/ZnO nanocomposites using Boehmeria nivea leaf extract. Biointerphases 1 November 2022; 19 (6): 061001. https://doi.org/10.1116/6.0003858
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