This study aims to explore the essential functional requirements associated with controlling the proliferation of microbes in the domain of textiles used in public health areas. Herein, three antimicrobial agents, specifically iodopropylbutylcarbamate (IPBC), 1-hydroxypyridine-2-thioketone zinc (ZPT), and 2-octyl-3-isothiazolinone (OIT), were chosen for fabric finishing based on their notable effectiveness, minimal toxicity, cost-efficiency, and chemical stability. Utilizing Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) as representative bacterial strains, the Minimum Inhibitory Concentration (MIC50) of individual and combined antimicrobial agents was measured, and their antimicrobial effectiveness was rigorously evaluated. Concurrently, the antimicrobial effectiveness, whiteness, and mechanical durability of the fabric following antimicrobial treatment were thoroughly examined. The results demonstrate that some combinations of the three antimicrobial agents elicit additive effects on both S. aureus and E. coli. Notably, at an equivalent ratio of IPBC, ZPT, and OIT and a total concentration of 0.2 wt. %, the inhibition rates against both bacterial strains surpass 99%. Upon application to nylon fabric, the treated material demonstrates significant antimicrobial properties, with minimal reduction observed in the whiteness and tensile strength of the treated nylon. This study provides practicable strategies relevant to the production of textiles endowed with antimicrobial properties.
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Research Article|
June 27 2024
Enhanced bactericidal performance of textiles through compound antimicrobial agents
Special Collection:
Special Topic Collection: Biointerface Science in China 2024
Yi Huang
;
Yi Huang
a)
(Data curation, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing)
1
Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Zhejiang University School of Medicine
, Hangzhou 310000, Chinaa)Author to whom correspondence should be addressed: huangyicy@zju.edu.cn
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Ying Li
;
Ying Li
(Data curation, Investigation, Methodology, Validation, Writing – original draft)
2
Zhejiang Hexin New Material Co., Ltd.
, Jiaxing 314000, China
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Kai-Bo Chen
;
Kai-Bo Chen
(Data curation, Investigation, Methodology)
1
Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Zhejiang University School of Medicine
, Hangzhou 310000, China
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Hang Zhang
Hang Zhang
(Data curation, Investigation, Methodology)
1
Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Zhejiang University School of Medicine
, Hangzhou 310000, China
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a)Author to whom correspondence should be addressed: huangyicy@zju.edu.cn
Biointerphases 19, 031003 (2024)
Article history
Received:
April 23 2024
Accepted:
May 28 2024
Connected Content
A companion article has been published:
Chemical trio imbues fabric with antimicrobial power
Citation
Yi Huang, Ying Li, Kai-Bo Chen, Hang Zhang; Enhanced bactericidal performance of textiles through compound antimicrobial agents. Biointerphases 1 May 2024; 19 (3): 031003. https://doi.org/10.1116/6.0003710
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