Although mammography is the gold standard for breast imaging, it leads to a high rate of biopsies of benign lesions and a significant false negative rate for women with dense breasts. A clinical breast‐imaging device, based on the principles of ultrasound tomography, is being developed in response to this imaging performance gap. The computed ultrasound risk evaluation (CURE) system has been designed with the clinical goal of providing fast, whole‐breast, operator‐independent imaging, capable of differentiating breast masses. In an initial assessment of its in vivo performance, 50 patients were examined with CURE. The following results were demonstrated: (i) tomographic imaging of breast architecture, (ii) in‐plane spatial resolution of 0.5 mm in reflection and 4 mm in transmission, (iii) imaging of breast masses in reflection and transmission mode (sound speed and attenuation, and (iv) differentiation of breast masses was shown to be feasible. These initial results indicate that operator‐independent, whole‐breast imaging and the detection and characterization of breast masses are feasible. Future studies will focus on improved detection and differentiation of masses with the long‐term goal of improving the specificity of breast exams. [The authors acknowledge financial support from the Karmanos Cancer Institute and the NIH (grant R43 CA108072‐01).]
Skip Nav Destination
Article navigation
November 2006
Meeting abstract. No PDF available.
November 01 2006
Whole breast imaging with ultrasound tomography: First clinical results at the Karmanos cancer institute
Neb Duric;
Neb Duric
Karmanos Cancer Inst., 4100 John R, Detroit, MI 48201
Search for other works by this author on:
Peter Littrup;
Peter Littrup
Karmanos Cancer Inst., 4100 John R, Detroit, MI 48201
Search for other works by this author on:
Earle Holsapple;
Earle Holsapple
Karmanos Cancer Inst., 4100 John R, Detroit, MI 48201
Search for other works by this author on:
Olsi Rama
Olsi Rama
Karmanos Cancer Inst., 4100 John R, Detroit, MI 48201
Search for other works by this author on:
J. Acoust. Soc. Am. 120, 3024 (2006)
Citation
Neb Duric, Peter Littrup, Earle Holsapple, Olsi Rama; Whole breast imaging with ultrasound tomography: First clinical results at the Karmanos cancer institute. J. Acoust. Soc. Am. 1 November 2006; 120 (5_Supplement): 3024. https://doi.org/10.1121/1.4787111
Download citation file:
68
Views
Citing articles via
All we know about anechoic chambers
Michael Vorländer
A survey of sound source localization with deep learning methods
Pierre-Amaury Grumiaux, Srđan Kitić, et al.
Does sound symbolism need sound?: The role of articulatory movement in detecting iconicity between sound and meaning
Mutsumi Imai, Sotaro Kita, et al.
Related Content
Clinical breast imaging with ultrasound tomography: A description of the SoftVue system
J Acoust Soc Am (April 2014)
Combining time of flight and diffraction tomography for high resolution breast imaging: Initial invivo results (L)
J. Acoust. Soc. Am. (September 2012)
ULTRASONIC IMAGING TECHNIQUES FOR BREAST CANCER DETECTION
AIP Conference Proceedings (February 2008)
High-resolution imaging without iteration: a fast and robust method for breast ultrasound tomography
J. Acoust. Soc. Am. (September 2011)
From laboratory to clinical trials: An odyssey of ultrasound inverse scattering imaging for breast cancer diagnosis
J Acoust Soc Am (November 2006)