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Journal Articles

Interstitial fluid flow in an engineered human lymph node stroma model modulates T cell egress and stromal change

Featured
Jennifer H. Hammel, Abhinav Arneja, Jessica Cunningham, Maosen Wang, Sophia Schumaecker, Yamilet Macias Orihuela, Tochukwu Ozulumba, Jonathan M. Zatorski, Thomas J. Braciale, Chance John Luckey, Rebecca R. Pompano, Jennifer M. Munson
Journal: APL Bioengineering
APL Bioeng. 9, 026105 (2025)
https://doi.org/10.1063/5.0247363
Published: April 2025
View articletitled, Interstitial fluid flow in an engineered human lymph node stroma model modulates T cell egress and stromal change
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Journal Articles

Epigenetic dynamics in meniscus cell migration and its zonal dependency in response to inflammatory conditions

Featured
Yize Zhang, Ellen Y. Zhang, Catherine Cheung, Yuna Heo, Bat-Ider Tumenbayar, Se-Hwan Lee, Yongho Bae, Su Chin Heo
Journal: APL Bioengineering
APL Bioeng. 9, 016109 (2025)
https://doi.org/10.1063/5.0239035
Published: February 2025
View articletitled, Epigenetic dynamics in meniscus cell migration and its zonal dependency in response to inflammatory conditions
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Journal Articles

Substrate stiffness modulates collective colony expansion of the social bacterium Myxococcus xanthus

Nuzhat Faiza, Roy Welch, Alison Patteson
Journal: APL Bioengineering
APL Bioeng. 9, 016104 (2025)
https://doi.org/10.1063/5.0226619
Published: January 2025
View articletitled, Substrate stiffness modulates collective colony expansion of the social bacterium Myxococcus xanthus
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Journal Articles

Intercellular junction-driven stromal cell stacking in a confined 3D microcavity

Avelino Dos Santos Da Costa, Hyuntae Jeong, Ramesh Subbiah, Kwideok Park, In-Suk Choi, Jennifer H. Shin
Journal: APL Bioengineering
APL Bioeng. 8, 046109 (2024)
https://doi.org/10.1063/5.0197187
Published: November 2024
View articletitled, Intercellular junction-driven stromal cell stacking in a confined 3D microcavity
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Journal Articles

A programmable platform for probing cell migration and proliferation

Editor’s Pick
Jillian Cwycyshyn, Cooper Stansbury, Walter Meixner, James B. Hoying, Lindsey A. Muir, Indika Rajapakse
Journal: APL Bioengineering
APL Bioeng. 8, 046106 (2024)
https://doi.org/10.1063/5.0209547
Published: October 2024
View articletitled, A programmable platform for probing cell migration and proliferation
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Journal Articles

Enhanced non-viral gene delivery via calcium phosphate/DNA co-precipitates with low-voltage pulse electroporation in NK-92 cells for immunocellular therapy

Featured
Che-Yung Kuan, I-Hsuan Yang, Chia-Ting Chang, Zhi-Yu Chen, Jhih-Ni Lin, Wei-Ting Kuo, Yu-Ying Lin, Andrew Yueh, Feng-Huei Lin
Journal: APL Bioengineering
APL Bioeng. 8, 036107 (2024)
https://doi.org/10.1063/5.0198191
Published: August 2024
View articletitled, Enhanced non-viral gene delivery via calcium phosphate/DNA co-precipitates with low-voltage pulse electroporation in NK-92 cells for immunocellular therapy
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Journal Articles

Computational modeling of the physical features that influence breast cancer invasion into adipose tissue

Yitong Zheng, Dong Wang, Garrett Beeghly, Claudia Fischbach, Mark D. Shattuck, Corey S. O'Hern
Journal: APL Bioengineering
APL Bioeng. 8, 036104 (2024)
https://doi.org/10.1063/5.0209019
Published: July 2024
View articletitled, Computational modeling of the physical features that influence breast cancer invasion into adipose tissue
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Journal Articles

Mutual antagonism between CD44 and integrins in glioblastoma cell traction and migration

Featured
Marcus D. Kelly, Matthew R. Pawlak, Kevin H. Zhan, Ghaidan A. Shamsan, Wendy R. Gordon, David J. Odde
Journal: APL Bioengineering
APL Bioeng. 8, 036102 (2024)
https://doi.org/10.1063/5.0203028
Published: July 2024
View articletitled, Mutual antagonism between CD44 and integrins in glioblastoma cell traction and migration
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Journal Articles

Dissecting TGF-β-induced glioblastoma invasion with engineered hyaluronic acid hydrogels

Featured
Kwasi Yeboa Amofa, Katherine Michelle Patterson, Jessica Ortiz, Sanjay Kumar
Journal: APL Bioengineering
APL Bioeng. 8, 026125 (2024)
https://doi.org/10.1063/5.0203213
Published: June 2024
View articletitled, Dissecting TGF-β-induced glioblastoma invasion with engineered hyaluronic acid hydrogels
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Journal Articles

Asymmetrical positioning of cell organelles reflects the cell chirality of mouse myoblast cells

Zeina Hachem, Courtney Hadrian, Lina Aldbaisi, Muslim Alkaabi, Leo Q. Wan, Jie Fan
Journal: APL Bioengineering
APL Bioeng. 8, 016119 (2024)
https://doi.org/10.1063/5.0189401
Published: March 2024
View articletitled, Asymmetrical positioning of cell organelles reflects the cell chirality of mouse myoblast cells
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Includes: Supplementary data
Journal Articles

SEM2: Introducing mechanics in cell and tissue modeling using coarse-grained homogeneous particle dynamics

Sandipan Chattaraj, Michele Torre, Constanze Kalcher, Alexander Stukowski, Simone Morganti, Alessandro Reali, Francesco Silvio Pasqualini
Journal: APL Bioengineering
APL Bioeng. 7, 046118 (2023)
https://doi.org/10.1063/5.0166829
Published: December 2023
View articletitled, SEM2: Introducing mechanics in cell and tissue modeling using coarse-grained homogeneous particle dynamics
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Includes: Supplementary data
Journal Articles

Endothelial cells metabolically regulate breast cancer invasion toward a microvessel

Scilight
Matthew L. Tan, Niaa Jenkins-Johnston, Sarah Huang, Brittany Schutrum, Sandra Vadhin, Abhinav Adhikari, Rebecca M. Williams, Warren R. Zipfel, Jan Lammerding, Jeffrey D. Varner, Claudia Fischbach
Journal: APL Bioengineering
APL Bioeng. 7, 046116 (2023)
https://doi.org/10.1063/5.0171109
Published: December 2023
View articletitled, Endothelial cells metabolically regulate breast cancer invasion toward a microvessel
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Includes: Supplementary data
Journal Articles

The yellow brick road to nuclear membrane mechanotransduction

Zhouyang Shen, Miklós Lengyel, Philipp Niethammer
Journal: APL Bioengineering
APL Bioeng. 6, 021501 (2022)
https://doi.org/10.1063/5.0080371
Published: March 2022
View articletitled, The yellow brick road to nuclear membrane mechanotransduction
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Journal Articles

Cell shape, and not 2D migration, predicts extracellular matrix-driven 3D cell invasion in breast cancer

Janani P. Baskaran, Anna Weldy, Justinne Guarin, Gabrielle Munoz, Polina H. Shpilker, Michael Kotlik, Nandita Subbiah, Andrew Wishart, Yifan Peng, Miles A. Miller, Lenore Cowen, Madeleine J. Oudin
Journal: APL Bioengineering
APL Bioeng. 4, 026105 (2020)
https://doi.org/10.1063/1.5143779
Published: May 2020
View articletitled, Cell shape, and not 2D migration, predicts extracellular matrix-driven 3D cell invasion in breast cancer
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Includes: Supplementary data
Journal Articles

Epithelial vertex models with active biochemical regulation of contractility can explain organized collective cell motility

Sarita Koride, Andrew J. Loza, Sean X. Sun
Journal: APL Bioengineering
APL Bioeng. 2, 031906 (2018)
https://doi.org/10.1063/1.5023410
Published: July 2018
View articletitled, Epithelial vertex models with active biochemical regulation of contractility can explain organized collective cell motility
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Includes: Supplementary data
Journal Articles

Fibroblast migration correlates with matrix softness. A study in knob-hole engineered fibrin

Christopher Y. Leon-Valdivieso, Jennifer Wedgwood, Enrique Lallana, Roberto Donno, Iwan Roberts, Matilde Ghibaudi, Annalisa Tirella, Nicola Tirelli
Journal: APL Bioengineering
APL Bioeng. 2, 036102 (2018)
https://doi.org/10.1063/1.5022841
Published: July 2018
View articletitled, Fibroblast migration correlates with matrix softness. A study in knob-hole engineered fibrin
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Includes: Supplementary data
Journal Articles

Anomalously diffusing and persistently migrating cells in 2D and 3D culture environments

Editor’s Pick
Igor D. Luzhansky, Alyssa D. Schwartz, Joshua D. Cohen, John P. MacMunn, Lauren E. Barney, Lauren E. Jansen, Shelly R. Peyton
Journal: APL Bioengineering
APL Bioeng. 2, 026112 (2018)
https://doi.org/10.1063/1.5019196
Published: June 2018
View articletitled, Anomalously diffusing and persistently migrating cells in 2D and 3D culture environments
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Includes: Supplementary data
Journal Articles

Contact guidance is cell cycle-dependent

Kamyar Esmaeili Pourfarhangi, Edgar Cardenas De La Hoz, Andrew R. Cohen, Bojana Gligorijevic
Journal: APL Bioengineering
APL Bioeng. 2, 031904 (2018)
https://doi.org/10.1063/1.5026419
Published: May 2018
View articletitled, Contact guidance is cell cycle-dependent
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Includes: Supplementary data
Journal Articles

Flexible and disposable paper- and plastic-based gel micropads for nematode handling, imaging, and chemical testing

Zach Njus, Taejoon Kong, Upender Kalwa, Christopher Legner, Matthew Weinstein, Shawn Flanigan, Jenifer Saldanha, Santosh Pandey
Journal: APL Bioengineering
APL Bioeng. 1, 016102 (2017)
https://doi.org/10.1063/1.5005829
Published: October 2017
View articletitled, Flexible and disposable paper- and plastic-based gel micropads for nematode handling, imaging, and chemical testing
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Includes: Supplementary data