We have developed a scanning superconducting quantum interference device (SQUID) microscope system with interchangeable sensor configurations for imaging magnetic fields of room-temperature (RT) samples with submillimeter resolution. The low-critical-temperature niobium-based monolithic SQUID sensors are mounted on the tip of a sapphire and thermally anchored to the helium reservoir. A sapphire window separates the vacuum space from the RT sample. A positioning mechanism allows us to adjust the sample-to-sensor spacing from the top of the Dewar. We achieved a sensor-to-sample spacing of , which could be maintained for periods of up to four weeks. Different SQUID sensor designs are necessary to achieve the best combination of spatial resolution and field sensitivity for a given source configuration. For imaging thin sections of geological samples, we used a custom-designed monolithic low- niobium bare SQUID sensor, with an effective diameter of , and achieved a field sensitivity of and a magnetic moment sensitivity of at a sensor-to-sample spacing of in the white noise region for frequencies above . Imaging action currents in cardiac tissue requires a higher field sensitivity, which can only be achieved by compromising spatial resolution. We developed a monolithic low- niobium multiloop SQUID sensor, with sensor sizes ranging from to , and achieved sensitivities of in the white noise region for frequencies above , respectively. For all sensor configurations, the spatial resolution was comparable to the effective diameter and limited by the sensor-to-sample spacing. Spatial registration allowed us to compare high-resolution images of magnetic fields associated with action currents and optical recordings of transmembrane potentials to study the bidomain nature of cardiac tissue or to match petrography to magnetic field maps in thin sections of geological samples.
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May 2005
Research Article|
April 15 2005
High-resolution room-temperature sample scanning superconducting quantum interference device microscope configurable for geological and biomagnetic applications Available to Purchase
L. E. Fong;
L. E. Fong
Vanderbilt University
, Nashville, Tennessee 37235
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J. R. Holzer;
J. R. Holzer
Vanderbilt University
, Nashville, Tennessee 37235
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K. K. McBride;
K. K. McBride
Vanderbilt University
, Nashville, Tennessee 37235
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E. A. Lima;
E. A. Lima
Vanderbilt University
, Nashville, Tennessee 37235
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F. Baudenbacher;
F. Baudenbacher
a)
Vanderbilt University
, Nashville, Tennessee 37235
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M. Radparvar
M. Radparvar
Hypres Inc.
, Elmsford, New York 10523
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L. E. Fong
Vanderbilt University
, Nashville, Tennessee 37235
J. R. Holzer
Vanderbilt University
, Nashville, Tennessee 37235
K. K. McBride
Vanderbilt University
, Nashville, Tennessee 37235
E. A. Lima
Vanderbilt University
, Nashville, Tennessee 37235
F. Baudenbacher
a)
Vanderbilt University
, Nashville, Tennessee 37235
M. Radparvar
Hypres Inc.
, Elmsford, New York 10523a)
Electronic mail: [email protected]
Rev. Sci. Instrum. 76, 053703 (2005)
Article history
Received:
December 02 2004
Accepted:
January 24 2005
Citation
L. E. Fong, J. R. Holzer, K. K. McBride, E. A. Lima, F. Baudenbacher, M. Radparvar; High-resolution room-temperature sample scanning superconducting quantum interference device microscope configurable for geological and biomagnetic applications. Rev. Sci. Instrum. 1 May 2005; 76 (5): 053703. https://doi.org/10.1063/1.1884025
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