Currently, it is challenging to investigate aneurismal hemodynamics based on current in vivo data such as Magnetic Resonance Imaging or Computed Tomography due to the limitations in both spatial and temporal resolutions. In this work, we investigate the use of modal analysis at various resolutions to examine its usefulness for analyzing blood flows in brain aneurysms. Two variants of Dynamic Mode Decomposition (DMD): (i) Hankel-DMD; and (ii) Optimized-DMD, are used to extract the time-dependent dynamics of blood flows during one cardiac cycle. First, high-resolution hemodynamic data in patient-specific aneurysms are obtained using Computational Fluid Dynamics. Second, the dynamics modes, along with their spatial amplitudes and temporal magnitudes are calculated using the DMD analysis. Third, an examination of DMD analyses using a range of spatial and temporal resolutions of hemodynamic data to validate the applicability of DMD for low-resolution data, similar to ones in clinical practices. Our results show that DMD is able to characterize the inflow jet dynamics by separating large-scale structures and flow instabilities even at low spatial and temporal resolutions. Its robustness in quantifying the flow dynamics using the energy spectrum is demonstrated across different resolutions in all aneurysms in our study population. Our work indicates that DMD can be used for analyzing blood flow patterns of brain aneurysms and is a promising tool to be explored in in vivo.
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January 2025
Research Article|
January 06 2025
Modal analysis of blood flows in saccular aneurysms
Thien-Tam Nguyen (Nguyễn Thiện Tâm)
;
Thien-Tam Nguyen (Nguyễn Thiện Tâm)
(Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft)
1
Department of Civil, Construction, and Environmental Engineering, North Dakota State University
, Fargo, North Dakota 58102, USA
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Davina Kasperski;
Davina Kasperski
(Conceptualization, Data curation, Formal analysis, Investigation, Methodology)
1
Department of Civil, Construction, and Environmental Engineering, North Dakota State University
, Fargo, North Dakota 58102, USA
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Phat Kim Huynh (Huỳnh Kim Phát)
;
Phat Kim Huynh (Huỳnh Kim Phát)
(Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation)
2
Department of Industrial and Systems Engineering, North Carolina A&T State University
, Greensboro, North Carolina 27411, USA
3
Department of Industrial and Management Systems Engineering, University of South Florida
, Tampa, Florida 33620, USA
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Trung Quoc Le (Lê Quốc Trung)
;
Trung Quoc Le (Lê Quốc Trung)
(Conceptualization, Investigation, Methodology, Project administration, Writing – review & editing)
3
Department of Industrial and Management Systems Engineering, University of South Florida
, Tampa, Florida 33620, USA
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Trung Bao Le (Lê Bảo Trung)
Trung Bao Le (Lê Bảo Trung)
a)
(Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Writing – original draft, Writing – review & editing)
1
Department of Civil, Construction, and Environmental Engineering, North Dakota State University
, Fargo, North Dakota 58102, USA
a)Author to whom correspondence should be addressed: [email protected]. URL: https://sites.google.com/view/complexfluidlab/
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a)Author to whom correspondence should be addressed: [email protected]. URL: https://sites.google.com/view/complexfluidlab/
Physics of Fluids 37, 011906 (2025)
Article history
Received:
October 10 2024
Accepted:
December 11 2024
Citation
Thien-Tam Nguyen, Davina Kasperski, Phat Kim Huynh, Trung Quoc Le, Trung Bao Le; Modal analysis of blood flows in saccular aneurysms. Physics of Fluids 1 January 2025; 37 (1): 011906. https://doi.org/10.1063/5.0243383
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