Existing research on interference effects predominantly focuses on rigid structures. However, studies based on rigid models tend to overlook the feedback of structural motions on the flow field, thus failing to capture the intrinsic dynamics of the interference effect induced by wind-induced structural vibrations. This paper provides a comprehensive analysis of the fluid–structure interaction mechanisms considering interference effects involving two parallel square prisms, employing large-eddy simulation (LES). Various factors, including wind speed, arrangement, and vibration amplitude, are meticulously considered in the analysis. The study utilized three-dimensional LES simulations, incorporating the narrowband synthesis random flow generator method for inlet turbulence generation and adjusted through the “feedback” approach to ensure accuracy and efficiency. The research highlighted different structural arrangements exhibited distinct interference effects, and the end effect of the structure could substantially modify the flow pattern at various heights. In the tandem arrangements, the study observed several flow phenomena, including early reattachment, attenuation of the end effect, premature formation of roll structures, increased turbulence in the flow field due to vibration, resulting in wider second leading-edge separation, and a fragmented wake flow on the downstream structure. For side-by-side arrangements, the “acceleration effect” was identified and found to be further intensified by structural vibrations. The vibration of the interfering structure was noted to cause changes in vortex shedding frequencies and alterations in the wake flow pattern. In addition, vibration would enhance the interference effect but increasing amplitude and wind speed might diminish the interference effect. Overall, this study offers valuable insight into the intricate interplay of factors influencing the aerodynamics of parallel structures across diverse arrangements and under varying conditions.

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