In this study, we assume that blood is assumed to be a viscoelastic and incompressible homogeneous media in which several uniform sized oxygen bubbles are uniformly distributed. Based on this, we establish a (3 + 1)-dimensional modified Kadomtsev–Petviashvili (mKP) equation to describe the long nonlinear pressure waves in the gas bubbles–liquid mixtures. Using bell polynomials, a new bilinear form of the mKP equation is constructed, and then the one- and two-soliton solutions of the equation are obtained by the Hirota method. Via the one-soliton solutions, parametric conditions of the existence of shock wave, elevation and depression solitons, and the Mach reflection characters in the mixtures are discussed. Soliton interactions have been discussed on the basis of the two-soliton solutions. We find that the (i) parallel elastic interactions can exist between the shock and elevation solitons; (ii) oblique elastic interactions can exist between the (a) shock and depression solitons and (b) the elevation and depression solitons; and (iii) oblique inelastic interactions can exist between the two depression solitons.
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