Atherosclerosis is an important cause of cardiovascular disease. The wall shear stress (WSS) is one of the key factors of plaque formation and dislodgement. Currently, WSS estimation is based on the measurement of the blood velocity gradient. However, due to the lack of flow field measurements in carotid stenosis vessels, the two distribution forms (parabolic and non-parabolic) commonly considered in numerical simulations could cause WSS estimates to differ by more than 40%, which could seriously affect the accuracy of mechanical analysis. This study applied three-dimensional (3D) printing technology to create an experimental model of real-structure carotid arteries. Microparticle image velocimetry was adopted to comprehensively measure blood velocity field data at the stenosis location, providing experimental validation of numerical simulation (Fluent; finite volume method) results. Then, the flow field was simulated at a normal human heart rate (45–120 beats per minute). The radial sectional velocity exhibited a plateau-like distribution with a similar velocity in the central region (more than 65% of the total channel width). This study provides an accurate understanding of the WSS at the carotid stenosis location and proposes a reliable method for the study of flow fields under various blood flow conditions.
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Study on the radial sectional velocity distribution and wall shear stress associated with carotid artery stenosis
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May 2022
Research Article|
May 10 2022
Study on the radial sectional velocity distribution and wall shear stress associated with carotid artery stenosis
Zhiyong Song (宋智勇)
;
Zhiyong Song (宋智勇)
a)
1
School of Civil and Resource Engineering, University of Science and Technology Beijing
, Beijing 100083, China
a)Author to whom correspondence should be addressed: [email protected]
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Pengrui Zhu (朱澎芮)
;
Pengrui Zhu (朱澎芮)
1
School of Civil and Resource Engineering, University of Science and Technology Beijing
, Beijing 100083, China
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Lianzhi Yang (杨连枝);
Lianzhi Yang (杨连枝)
1
School of Civil and Resource Engineering, University of Science and Technology Beijing
, Beijing 100083, China
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Zhaohui Liu (刘朝晖);
Zhaohui Liu (刘朝晖)
2
Department of Neurosurgery, Hainan General Hospital
, Haikou 570311, Hainan, China
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Hua Li (李华);
Hua Li (李华)
1
School of Civil and Resource Engineering, University of Science and Technology Beijing
, Beijing 100083, China
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Weiyao Zhu (朱维耀)
Weiyao Zhu (朱维耀)
1
School of Civil and Resource Engineering, University of Science and Technology Beijing
, Beijing 100083, China
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a)Author to whom correspondence should be addressed: [email protected]
Physics of Fluids 34, 051904 (2022)
Article history
Received:
January 19 2022
Accepted:
March 26 2022
Citation
Zhiyong Song, Pengrui Zhu, Lianzhi Yang, Zhaohui Liu, Hua Li, Weiyao Zhu; Study on the radial sectional velocity distribution and wall shear stress associated with carotid artery stenosis. Physics of Fluids 1 May 2022; 34 (5): 051904. https://doi.org/10.1063/5.0085796
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