The dispersion of viral droplets plays a key role in the transmission of COVID-19. In this work, we analyze the dispersion of cough-generated droplets in the wake of a walking person for different space sizes. The air flow is simulated by solving the Reynolds-averaged Navier–Stokes equations, and the droplets are modeled as passive Lagrangian particles. Simulation results show that the cloud of droplets locates around and below the waist height of the manikin after 2 s from coughing, which indicates that kids walking behind an infectious patient are exposed to higher transmission risk than adults. More importantly, two distinct droplet dispersion modes occupying significantly different contamination regions are discovered. A slight change of space size is found being able to trigger the transition of dispersion modes even though the flow patterns are still similar. This shows the importance of accurately simulating the air flow in predicting the dispersion of viral droplets and implies the necessity to set different safe-distancing guidelines for different environments.

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