Protocol for structure determination of unknowns by EI mass spectrometry. IV. Diagnostic ions in the mass spectra of polyfunctional compounds with hydroxyl, keto, carboxyl, mercapto and/or amine groups Available to Purchase

Key ions for structure elucidation in the electron ionization mass spectra of di- and polyfunctional compounds containing only a single functional group, such as hydroxyl, mercapto-, carbonyl, carboxyl, and amino functionality are revealed. They are attached to aliphatic, alicyclic, aromatic hydrocarbons and their hetero analogs. The analysis is extended to the spectra of polyfunctional compounds encompassing different functional groups including sugars, hydroxy acids, keto acids and amino acids. The potential of mass spectrometry for structure elucidation via chemical modification of these compounds is revealed as well. Diagnostic ions in the mass spectra of alkyl, trimethylsilyl, acetyl, trifluoroacetyl and methoxycarbonyl derivatives are identified.