Jacob Israelachvili in his famous book Intermolecular and Surface Forces1 writes—commenting on the observed increase in the dielectric constant and in the proton conductivity on freezing—that “to understand the secrets of liquid water one may first have to unravel those of ice.” This Special Topic on the “Chemical Physics of Supercooled Water” in The Journal of Chemical Physics has been ideated, planned, and realized with the idea that not ice, but supercooled water, holds promises for unravelling the peculiar physics originating from the directionality and the strength of the water-water interaction. It is in supercooled states that the famous thermodynamic anomalies of water show up in full glory. Indeed in water, differently from other liquids and despite the reduction in thermal vibrations, fluctuations in density and enthalpy significantly rise on cooling, as revealed by the temperature dependence of the compressibility and specific heat. Supercooling thus acts as a magnifying lens allowing us to explore the origin of water’s peculiar dynamic and thermodynamic behavior. However, the study of supercooled water is often hampered due to its metastability with respect to crystalline ices. Especially, if long measurements are required, it is only possible to study supercooled water down to temperatures of 255 K as in Ref. 2 on D2O expansivity, or to 235 K as in the study of the O–O radial density functions.3 Crystallization rates rise so rapidly with decreasing temperature that a boundary for the possibility to study supercooled water has been set, below which noncrystalline water can no longer be studied. This boundary is, however, only a soft limit and depends on the timescale, where typically minutes or seconds are used to set the line. An understanding of nucleation and ice growth is of key importance in this context.4–7 When beating crystallization through ultrafast cooling of liquid droplets or through vapor-deposition of water on cold substrates, the amorphous solid state can be reached. Such amorphous samples may also crystallize, since crystallization rates rapidly increase upon heating, typically near 150 K. References 8 and 9 go beyond this limit and determine nucleation and crystallization rates in transiently heated films for temperatures up to 230 K.

In order to be able to measure the properties of noncrystalline water in its “no-man’s land,” quite often, solutes and/or confinement are employed instead of ultrafast experiments. References 10–13 employ salt solutions, Ref. 14 investigates polyalcohol solutions, Ref. 15 studies the monoalcohol methanol, and Ref. 16 studies the cryoprotecting sugar trehalose. References 17–19 study supercooled water in confinement, and Ref. 20 even combines the two strategies, putting confined salt solutions under scrutiny.

While it is appealing to study confinement and aqueous solutions because water rarely occurs in its pure form in nature, care needs to be taken to extrapolate from such studies to the properties of pure H2O. Certainly, many of water’s properties are affected by confinement, and it is even possible to render water unfreezable due to the interaction with its surroundings. This is often the case for hydration water, which is studied in Refs. 16 and 21–23.

In this collection the physical origins behind the increase in the density and enthalpy fluctuations are discussed.24 The presence of distinct local structures, competing to minimise the Gibbs free energy, characterised by differences in their local density and local potential energy may provide an accurate modelling of water’s thermodynamics.2,25–27 Some of the articles discuss how to identify these structures,3,28–30 how to distinguish them from ice-like structures,31 and how to decipher their contribution to the anomalies of water.32 

Central in this line of research is the detection of correlation between the spatial ordering of these local structures, a correlation that would indicate the possibility of a true phase separation in the no-man’s land.26,33–35 Beside temperature and pressure changes, perturbation of the water network via addition of small solute molecules,10–12,14,20,36 even active ones,37 offers an alternative way of shifting the equilibrium between different local structures in a controlled way.

Supercooled water can also be studied in a tiny temperature window above the glass transition temperature, just before crystallization takes place. Below the crystallization line, noncrystalline water can be studied as an amorphous solid or as an ultraviscous liquid in a tiny window above the glass transition temperature. In this low-temperature regime, first-order like transitions occur, where the density changes suddenly by 25%. By contrast, supercooled water above the no-man’s land does not experience such a transition, but rather a continuous change. That is, one cannot speak about two distinct types of liquid water above 200 K as pointed out in Ref. 38, but this could be different near 150 K. The reversible interconversion between the low- and high-density amorphous ices is thought to be low temperature proxy of a possible liquid-liquid transition that might take place just below the crystallization line and within the no-man’s land.

Several articles in this collection are devoted to the study of water polyamorphic structures and to the connections, if any, of these structures with the liquid state. Amorphous states can be generated by vapor deposition, hyperquenching, pressure amorphization,39 and interconversion of different amorphous states.40 Also, in this low-temperature regime, aqueous solutions may be employed to possibly reach higher temperatures without crystallization. The stable crystalline structures are then often clathrate hydrates or even chiral hydrates rather than ice Ih or high-pressure ice phases, and so the study of hydrates and their behavior in comparison with pure ices and supercooled water is of interest.30,39,41–43 The relation of the sharp polyamorphic transition with a possible first order liquid-liquid transition is tackled in this special topic from quite different angles.2,10,14,27,40,44,45 Needless to say, the investigation of out-of-equilibrium systems requires novel experimental41 and theoretical approaches.44,45

The investigation of ice,46 ice nucleation, and ice growth rate4–9,47 as a function of temperature, pressure, and impurities is another crucial topic discussed in the collection, a topic of relevance for basic science research and climate models, as well as for weather forecasts. In fact, the question whether clouds remain supercooled, crystallize partly or fully, and whether the droplet freezes from the inside outwards or from the outside inwards are crucial for our understanding of their reflective properties, which govern the cooling effect that clouds have on our climate. Indeed, water droplets in the atmosphere are often in metastable conditions. This requires control of the proper order parameters31 and of several delicate quantities48 entering in the nucleation rate.

The glassy dynamics of water molecules in supercooled states is also a key feature to understand water’s complex behaviour. In fact, thermodynamic and structural modifications that water undergoes upon supercooling in the bulk phase, in confinement and in solutions—including solutions of biomolecules—strongly affect the slow dynamics and the dynamic crossovers observed in water upon decreasing temperature. This topic is here discussed in bulk, under confinement and in solutions,12,13,15,17,19,49 as well as in the proximity of biomolecules.16,21–23,50,51 These articles focus on glassy dynamics (both α and secondary relaxations) in pure and in biological-hydration water. Some articles also study the onset of a super-slow relaxation connected to the coupling with the dynamics of the biomolecule. The influence of hydrophobicity on the diffusion of small spheroidal particles is discussed in Ref. 52.

In total, the present collection encompasses 51 articles, testifying the importance of water and aqueous solutions in sciences and our environment, both on Earth and in space. The research described in these articles certainly helps to push the forefront of our understanding of the chemical physics of supercooled water. Nonetheless, more questions than the ones answered still remain open, as pointed out in several concluding sections in this collection. In this sense, this special collection will hopefully be a stimulus for further research and trigger scientific discourse that will bring the field forward.

We thank the authors of the articles included in this Special Topic Collection for their contributions, and we thank the journal editors and the editorial staff of The Journal of Chemical Physics for their invaluable assistance.

1.
J. N.
Israelachvili
,
Intermolecular and Surface Forces
(
Academic Press
,
2015
).
2.
A.
Blahut
,
J.
Hykl
,
P.
Peukert
,
V.
Vins
, and
J.
Hruby
, “
Relative density and isobaric expansivity of cold and supercooled heavy water from 254 to 298 K and up to 100 MPa
,”
J. Chem. Phys.
151
(
3
),
034505
(
2019
).
3.
H.
Pathak
,
A.
Späh
,
K. H.
Kim
,
I.
Tsironi
,
D.
Mariedahl
,
M.
Blanco
,
S.
Huotari
,
V.
Honkimäki
, and
A.
Nilsson
, “
Intermediate range O–O correlations in supercooled water down to 235 K
,”
J. Chem. Phys.
150
(
22
),
224506
(
2019
).
4.
R.
Shi
and
H.
Tanaka
, “
Homogeneous nucleation of ferroelectric ice crystal driven by spontaneous dipolar ordering in supercooled TIP5P water
,”
J. Chem. Phys.
151
(
2
),
024501
(
2019
).
5.
A.
Soni
and
G. N.
Patey
, “
Simulations of water structure and the possibility of ice nucleation on selected crystal planes of K-feldspar
,”
J. Chem. Phys.
150
(
21
),
214501
(
2019
).
6.
F.
Leoni
,
R.
Shi
,
H.
Tanaka
, and
J.
Russo
, “
Crystalline clusters in mW water: Stability, growth, and grain boundaries
,”
J. Chem. Phys.
151
(
4
),
044505
(
2019
).
7.
P. M.
de Hijes
,
J. R.
Espinosa
,
C.
Vega
, and
E.
Sanz
, “
Ice growth rate: Temperature dependence and effect of heat dissipation
,”
J. Chem. Phys.
151
(
4
),
044509
(
2019
).
8.
G. A.
Kimmel
,
Y.
Xu
,
A.
Brumberg
,
N. G.
Petrik
,
R. S.
Smith
, and
B. D.
Kay
, “
Homogeneous ice nucleation rates and crystallization kinetics in transiently-heated, supercooled water films from 188 K to 230 K
,”
J. Chem. Phys.
150
(
20
),
204509
(
2019
).
9.
R. S.
Smith
,
C.
Yuan
,
N. G.
Petrik
,
G. A.
Kimmel
, and
B. D.
Kay
, “
Crystallization growth rates and front propagation in amorphous solid water films
,”
J. Chem. Phys.
150
(
21
),
214703
(
2019
).
10.
L. E.
Bove
,
F.
Pietrucci
,
A. M.
Saitta
,
S.
Klotz
, and
J.
Teixeira
, “
On the link between polyamorphism and liquid-liquid transition: The case of salty water
,”
J. Chem. Phys.
151
(
4
),
044503
(
2019
).
11.
K.
Imrichova
,
L.
Veseli
,
T. M.
Gasser
,
T.
Loerting
,
V.
Nedela
, and
D.
Heger
, “
Vitrification and increase of basicity in between ice Ih crystals in rapidly frozen dilute NaCl aqueous solutions
,”
J. Chem. Phys.
151
(
1
),
014503
(
2019
).
12.
P.
Munzner
,
L.
Hoffmann
,
R.
Bohmer
, and
C.
Gainaru
, “
Deeply supercooled aqueous LiCl solution studied by frequency-resolved shear rheology
,”
J. Chem. Phys.
150
(
23
),
234505
(
2019
).
13.
T.
Kikutsuji
,
K.
Kang
, and
N.
Matubayasi
, “
Diffusion dynamics of supercooled water modeled with the cage-jump motion and hydrogen-bond rearrangement
,”
J. Chem. Phys.
150
(
20
),
204502
(
2019
).
14.
Y.
Suzuki
, “
Effect of oh groups on the polyamorphic transition of polyol aqueous solutions
,”
J. Chem. Phys.
150
(
22
),
224508
(
2019
).
15.
C.
Corsaro
,
E.
Fazio
, and
D.
Mallamace
, “
The Stokes-Einstein relation in water/methanol solutions
,”
J. Chem. Phys.
150
(
23
),
234506
(
2019
).
16.
A.
Iorio
,
G.
Camisasca
,
M.
Rovere
, and
P.
Gallo
, “
Characterization of hydration water in supercooled water-trehalose solutions: The role of the hydrogen bonds network
,”
J. Chem. Phys.
151
(
4
),
044507
(
2019
).
17.
A. I.
Kolesnikov
,
L. M.
Anovitz
,
F. C.
Hawthorne
,
A.
Podlesnyak
, and
G. K.
Schenter
, “
Effect of fine-tuning pore structures on the dynamics of confined water
,”
J. Chem. Phys.
150
(
20
),
204706
(
2019
).
18.
E.
Stefanutti
,
L. E.
Bove
,
F. G.
Alabarse
,
G.
Lelong
,
F.
Bruni
, and
M. A.
Ricci
, “
Vibrational dynamics of confined supercooled water
,”
J. Chem. Phys.
150
(
22
),
224504
(
2019
).
19.
V.
De Michele
,
M.
Levantino
, and
A.
Cupane
, “
Hysteresis in the temperature dependence of the IR bending vibration of deeply cooled confined water
,”
J. Chem. Phys.
150
(
22
),
224509
(
2019
).
20.
M. P.
Longinotti
,
V.
Fuentes-Landete
,
T.
Loerting
, and
H. R.
Corti
, “
Glass transition of LiCI aqueous solutions confined in mesoporous silica
,”
J. Chem. Phys.
151
(
6
),
064509
(
2019
).
21.
S.
Cerveny
and
J.
Swenson
, “
Water dynamics in the hydration shells of biological and non-biological polymers
,”
J. Chem. Phys.
150
(
23
),
234904
(
2019
).
22.
K.
Sasaki
,
I.
Popov
, and
Y.
Feldman
, “
Water in the hydrated protein powders: Dynamic and structure
,”
J. Chem. Phys.
150
(
20
),
204504
(
2019
).
23.
S.
Capaccioli
,
K. L.
Ngai
,
S.
Ancherbak
,
M.
Bertoldo
,
G.
Ciampalini
,
M. S.
Thayyil
, and
L.-M.
Wang
, “
The JG β-relaxation in water and impact on the dynamics of aqueous mixtures and hydrated biomolecules
,”
J. Chem. Phys.
151
(
3
),
034504
(
2019
).
24.
J. M. M.
de Oca
,
S. R.
Accordino
,
G. A.
Appignanesi
,
P. H.
Handle
, and
F.
Sciortino
, “
Size dependence of dynamic fluctuations in liquid and supercooled water
,”
J. Chem. Phys.
150
(
14
),
144505
(
2019
).
25.
F.
Caupin
and
M. A.
Anisimov
, “
Thermodynamics of supercooled and stretched water: Unifying two-structure description and liquid-vapor spinodal
,”
J. Chem. Phys.
151
(
3
),
034503
(
2019
).
26.
P.
Mausbach
,
H.-O.
May
, and
R.
George
, “
Thermodynamic metric geometry of the two-state ST2 model for supercooled water
,”
J. Chem. Phys.
151
(
6
),
064503
(
2019
).
27.
F.
Mallamace
,
C.
Corsaro
,
D.
Mallamace
,
E.
Fazio
, and
S.-H.
Chen
, “
Some considerations on the water polymorphism and the liquid-liquid transition by the density behavior in the liquid phase
,”
J. Chem. Phys.
151
(
4
),
044504
(
2019
).
28.
G.
Camisasca
,
D.
Schlesinger
,
I.
Zhovtobriukh
,
G.
Pitsevich
, and
L. G. M.
Pettersson
, “
A proposal for the structure of high- and low-density fluctuations in liquid water
,”
J. Chem. Phys.
151
(
3
),
034508
(
2019
).
29.
G.
Camisasca
,
H.
Pathak
,
K. T.
Wikfeldt
, and
L. G. M.
Pettersson
, “
Radial distribution functions of water: Models vs experiments
,”
J. Chem. Phys.
151
(
4
),
044502
(
2019
).
30.
S.
Funke
,
F.
Sebastiani
,
G.
Schwaab
, and
M.
Havenith
, “
Spectroscopic fingerprints in the low frequency spectrum of ice (Ih), clathrate hydrates, supercooled water, and hydrophobic hydration reveal similarities in the hydrogen bond network motifs
,”
J. Chem. Phys.
150
(
22
),
224505
(
2019
).
31.
M.
Matsumoto
,
T.
Yagasaki
, and
H.
Tanaka
, “
A Bayesian approach for identification of ice Ih, ice Ic, high density, and low density liquid water with a torsional order parameter
,”
J. Chem. Phys.
150
(
21
),
214504
(
2019
).
32.
F.
Martelli
, “
Unravelling the contribution of local structures to the anomalies of water: The synergistic action of several factors
,”
J. Chem. Phys.
150
(
9
),
094506
(
2019
).
33.
P.
Chitnelawong
,
F.
Sciortino
, and
P. H.
Poole
, “
The stability-limit conjecture revisited
,”
J. Chem. Phys.
150
(
23
),
234502
(
2019
).
34.
C. A.
Cerdeirina
,
J.
Troncoso
,
D.
Gonzalez-Salgado
,
P. G.
Debenedetti
, and
H. E.
Stanley
, “
Water’s two-critical-point scenario in the Ising paradigm
,”
J. Chem. Phys.
150
(
24
),
244509
(
2019
).
35.
R. S.
Singh
,
J. C.
Palmer
,
A. Z.
Panagiotopoulos
, and
P. G.
Debenedetti
, “
Thermodynamic analysis of the stability of planar interfaces between coexisting phases and its application to supercooled water
,”
J. Chem. Phys.
150
(
22
),
224503
(
2019
).
36.
T.
Yagasaki
,
M.
Matsumoto
, and
H.
Tanaka
, “
Liquid-liquid separation of aqueous solutions: A molecular dynamics study
,”
J. Chem. Phys.
150
(
21
),
214506
(
2019
).
37.
V.
Teboul
and
G.
Rajonson
, “
Simulations of supercooled water under passive or active stimuli
,”
J. Chem. Phys.
150
(
21
),
214505
(
2019
).
38.
A. K.
Soper
, “
Is water one liquid or two?
,”
J. Chem. Phys.
150
(
23
),
234503
(
2019
).
39.
O.
Andersson
,
H.
Paulo
,
B. B.
Carvalho
,
Y.-J.
Hsu
, and
H.
Ulrich
, “
Transitions in pressure-amorphized clathrate hydrates akin to those of amorphous ices
,”
J. Chem. Phys.
151
(
1
),
014502
(
2019
).
40.
G.
Shen
,
J. S.
Smith
,
C.
Kenney-Benson
, and
R. A.
Ferry
, “
In situ x-ray diffraction study of polyamorphism in H2O under isothermal compression and decompression
,”
J. Chem. Phys.
150
(
24
),
244201
(
2019
).
41.
L. J.
Plaga
,
A.
Raidt
,
V. F.
Landete
,
K.
Amann-Winkel
,
B.
Massani
,
T. M.
Gasser
,
C.
Gainaru
,
T.
Loerting
, and
R.
Böhmer
, “
Amorphous and crystalline ices studied by dielectric spectroscopy
,”
J. Chem. Phys.
150
(
24
),
244501
(
2019
).
42.
B.
Massani
,
L. J.
Conway
,
A.
Hermann
, and
J.
Loveday
, “
On a new nitrogen sX hydrate from ice XVII
,”
J. Chem. Phys.
151
(
10
),
104305
(
2019
).
43.
M. H.
Factorovich
,
P. M.
Naullage
, and
V.
Molinero
, “
Can clathrates heterogeneously nucleate ice?
,”
J. Chem. Phys.
151
(
11
),
114707
(
2019
).
44.
P. H.
Handle
,
F.
Sciortino
, and
N.
Giovambattista
, “
Glass polymorphism in TIP4P/2005 water: A description based on the potential energy landscape formalism
,”
J. Chem. Phys.
150
(
24
),
244506
(
2019
).
45.
N.
Giovambattista
,
F. W.
Starr
, and
P. H.
Poole
, “
State variables for glasses: The case of amorphous ice
,”
J. Chem. Phys.
150
(
22
),
224502
(
2019
).
46.
S.
Rasti
and
J.
Meyer
, “
Importance of zero-point energy for crystalline ice phases: A comparison of force fields and density functional theory
,”
J. Chem. Phys.
150
(
23
),
234504
(
2019
).
47.
M.
Nachbar
,
D.
Duft
, and
T.
Leisner
, “
The vapor pressure of liquid and solid water phases at conditions relevant to the atmosphere
,”
J. Chem. Phys.
151
(
6
),
064504
(
2019
).
48.
S. M. A.
Malek
,
P. H.
Poole
, and
I.
Saika-Voivod
, “
Surface tension of supercooled water nanodroplets from computer simulations
,”
J. Chem. Phys.
150
(
23
),
234507
(
2019
).
49.
Y.
Hachiya
,
T.
Uneyama
,
T.
Kaneko
, and
T.
Akimoto
, “
Unveiling diffusive states from center-of-mass trajectories in glassy dynamics
,”
J. Chem. Phys.
151
(
3
),
034502
(
2019
).
50.
S.
Corezzi
,
M.
Paolantoni
,
P.
Sassi
,
A.
Morresi
,
D.
Fioretto
, and
L.
Comez
, “
Trehalose-induced slowdown of lysozyme hydration dynamics probed by EDLS spectroscopy
,”
J. Chem. Phys.
151
(
1
),
015101
(
2019
).
51.
M. A. F.
dos Santos
,
M. A.
Habitzreuter
,
M. H.
Schwade
,
R.
Borrasca
,
M.
Antonacci
,
G. K.
Gonzatti
,
P. A.
Netz
, and
M. C.
Barbosa
, “
Dynamical aspects of supercooled TIP3P-water in the grooves of DNA
,”
J. Chem. Phys.
150
(
23
),
235101
(
2019
).
52.
N. K.
Marath
and
J. S.
Wettlaufer
, “
Hydrodynamic interactions and the diffusivity of spheroidal particles
,”
J. Chem. Phys.
151
(
2
),
024107
(
2019
).