The photofragmentation of protonated tryptophan has been investigated in a unique experimental setup, in which ion and neutral issued from the photofragmentation are detected in coincidence, in time and in position. From these data are extracted the kinetic energy, the number of neutral fragments associated with an ion, their masses, and the order of the fragmentation steps. Moreover, the fragmentation time scale ranging from tens of nanoseconds to milliseconds is obtained. From all these data, a comprehensive fragmentation mechanism is proposed.

1.
J. B.
Fenn
,
M.
Mann
,
C. K.
Meng
,
S. F.
Wong
, and
C. M.
Whitehouse
,
Mass Spectrom. Rev.
9
,
37
(
1990
).
2.
M.
Karas
,
U.
Bahr
, and
F.
Hillenkamp
,
Int. J. Mass Spectrom. Ion Process.
92
,
231
(
1989
).
3.
M. J.
Poke
,
S.
Beranova
,
M. J.
Nold
, and
C.
Wesderniotiss
,
J. Mass Spectrom.
31
,
1073
(
1996
);
[PubMed]
S.
Beranova
,
J.
Cai
, and
C.
Wesdemiotis
,
J. Am. Chem. Soc.
117
,
9492
(
1995
).
4.
T.
Chakraborty
,
A. I. S.
Holm
,
P.
Hvelplund
,
S. B.
Nielsen
,
J.-C.
Poully
,
E. S.
Worm
, and
E. R.
Williams
,
J. Am. Soc. Mass Spectrom.
17
,
1675
(
2006
).
5.
J.
Laskin
and
C.
Lifshitz
,
J. Mass Spectrom.
36
,
459
(
2001
).
6.
R. A.
Zubarev
,
N. L.
Kelleher
, and
F. W.
McLafferty
,
J. Am. Chem. Soc.
120
,
3265
(
1998
);
K.
Breuker
,
H.
Oh
,
B. A.
Cerda
,
D. M.
Horn
, and
F. W.
McLafferty
,
Eur. J. Mass Spectrom.
8
,
177
(
2002
).
7.
Z. Q.
Guan
,
N. L.
Kelleher
,
P. B.
Oconnor
,
D. J.
Aaserud
,
D. P.
Little
, and
F. W.
McLafferty
,
Int. J. Mass Spectrom. Ion Process.
158
,
357
(
1996
);
E. R.
Williams
,
J. J. P.
Furlong
, and
F. W.
McLafferty
,
J. Am. Soc. Mass Spectrom.
1
,
288
(
1990
);
[PubMed]
E. R.
Williams
and
F. W.
McLafferty
,
J. Am. Soc. Mass Spectrom.
1
,
361
(
1990
).
[PubMed]
8.
F.
Rogalewicz
,
Y.
Hoppilliard
, and
G.
Ohanessian
,
Int. J. Mass. Spectrom.
195/196
,
565
(
2000
).
9.
H.
Lioe
,
R. A. J.
O’Hair
, and
G. E.
Reid
,
J. Am. Soc. Mass Spectrom.
15
,
65
(
2004
).
10.
H.
El Aribi
,
G.
Orlova
,
A. C.
Hopkinson
, and
K. W. M.
Siu
,
J. Phys. Chem. A
108
,
3844
(
2004
).
11.
F. O.
Talbot
,
T.
Tabarin
,
R.
Antoine
,
M.
Broyer
, and
P.
Dugourd
,
J. Chem. Phys.
122
,
074310
(
2005
).
12.
H.
Kang
,
C.
Dedonder-Lardeux
,
C.
Jouvet
,
S.
Martrenchard
,
G.
Gregoire
,
C.
Desfrancois
,
J. P.
Schermann
,
M.
Barat
, and
J. A.
Fayeton
,
Phys. Chem. Chem. Phys.
6
,
2628
(
2004
).
13.
D.
Nolting
,
C.
Marian
, and
R.
Weinkauf
,
Phys. Chem. Chem. Phys.
6
,
2633
(
2004
).
14.
G.
Gregoire
,
H.
Kang
,
C.
Dedonder-Lardeux
,
C.
Jouvet
,
C.
Desfrancois
,
D.
Onidas
,
V.
Lepere
, and
J. A.
Fayeton
,
Phys. Chem. Chem. Phys.
8
,
122
(
2006
);
[PubMed]
G.
Gregoire
,
C.
Jouvet
,
C.
Dedonder
, and
A. L.
Sobolewski
,
Chem. Phys.
324
,
398
(
2006
).
15.
H.
Kang
,
C.
Jouvet
,
C.
Dedonder-Lardeux
,
S.
Martrenchard
,
C.
Charriere
,
G.
Gregoire
,
C.
Desfrancois
,
J. P.
Schermann
,
M.
Barat
, and
J. A.
Fayeton
,
J. Chem. Phys.
122
,
084307
(
2005
).
16.
M.
Barat
,
J. C.
Brenot
,
H.
Dunet
,
J. A.
Fayeton
, and
Y. J.
Picard
,
J. Chem. Phys.
110
,
10758
(
1999
);
M.
Barat
,
J. C.
Brenot
,
H.
Dunet
,
J. A.
Fayeton
, and
Y. J.
Picard
,
J. Chem. Phys.
113
,
1061
(
2000
);
M.
Barat
,
J. C.
Brenot
,
J. A.
Fayeton
, and
Y. J.
Picard
,
J. Chem. Phys.
117
,
1497
(
2002
).
17.
H. B.
Pedersen
,
D.
Strasser
,
S.
Ring
,
O.
Heber
,
M. L.
Rappaport
,
Y.
Rudich
,
I.
Sagi
, and
D.
Zajfman
,
Phys. Rev. Lett.
87
,
055001
(
2001
).
18.
H. B.
Pedersen
,
D.
Stasser
,
O.
Heber
,
M. L.
Rappaport
, and
D.
Zajfman
,
Phys. Rev. A
65
,
042703
(
2002
).
19.
H. B.
Pedersen
,
D.
Stasser
,
B.
Amarant
,
O.
Heber
,
M. L.
Rappaport
, and
D.
Zajfman
,
Phys. Rev. A
65
,
042704
(
2002
).
20.
V.
Lepere
,
I. M.
Ismail
,
M.
Barat
,
J. A.
Fayeton
,
Y. J.
Picard
,
K.
Wohrer
,
C.
Jouvet
, and
S.
Martrenchard
,
J. Chem. Phys.
123
,
174307
(
2005
).
21.
M. J.
Frisch
,
G. W.
Trucks
,
H. B.
Schlegel
 et al., GAUSSIAN 98, Gaussian, Inc., Pittsburgh, PA,
1998
.
22.
G.
Gregoire
,
C.
Jouvet
,
C.
Dedonder
, and
A. L.
Sobolewski
,
J. Am. Chem. Soc.
129
,
6223
(
2007
).
23.
Z. B.
Maksic
and
B.
Kovacevic
,
Chem. Phys. Lett.
307
,
497
(
1999
).
24.
J. U.
Andersen
,
H.
Cederquist
,
J. S.
Forster
 et al.,
Phys. Chem. Chem. Phys.
6
,
2676
(
2004
).
25.
H.
Kang
,
C.
Dedonder-Lardeux
,
C.
Jouvet
,
G.
Gregoire
,
C.
Desfrancois
,
J. P.
Schermann
,
M.
Barat
, and
J. A.
Fayeton
,
J. Phys. Chem. A
109
,
2417
(
2005
);
[PubMed]
H.
Kang
,
C.
Jouvet
,
C.
Dedonder-Lardeux
,
S.
Martrenchard
,
G.
Gregoire
,
C.
Desfrancois
,
J. P.
Schermann
,
M.
Barat
, and
J. A.
Fayeton
,
Phys. Chem. Chem. Phys.
7
,
394
(
2005
).
[PubMed]
26.
T. R.
Rizzo
,
Y. D.
Park
,
L. A.
Peteanu
, and
D. H.
Levy
,
J. Chem. Phys.
84
,
2534
(
1986
).
27.
O. V.
Boyarkin
,
S. R.
Mercier
,
A.
Kamariotis
, and
T. R.
Rizzo
,
J. Am. Chem. Soc.
128
,
2816
(
2006
).
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