Photoacoustic imaging is a hybrid imaging approach that combines the advantages of optical and ultrasonic imaging in one modality. However, for comprehensive tissue characterization, optical contrast alone is not always sufficient. In this study, we combined photoacoustic imaging with high-resolution ultrasound and shear wave elastography. The multi-modal system can calculate optical absorption, acoustic reflection, and stiffness volumetrically. We constructed a multi-modal phantom with contrast for each imaging modality to test the system’s performance. Experimental results indicate that the system successfully visualizes the embedded structures. We envision that the system will lead to more comprehensive tissue characterization for cancer screening and diagnosis.
Volumetric tri-modal imaging with combined photoacoustic, ultrasound, and shear wave elastography
Note: This paper is part of the Special Topic on Non-Invasive and Non-Destructive Methods and Applications Part I: Festschrift.
Emily Zheng, Huijuan Zhang, Wentao Hu, Marvin M. Doyley, Jun Xia; Volumetric tri-modal imaging with combined photoacoustic, ultrasound, and shear wave elastography. J. Appl. Phys. 21 July 2022; 132 (3): 034902. https://doi.org/10.1063/5.0093619
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