The mechanisms underlying the growth and rupture of aneurysms are poorly understood. Although the wall shear stress (WSS) in elastic aneurysm models is examined using fluid-structure interaction (FSI) simulations, it has not been sufficiently validated using experimental modalities, such as particle image velocimetry (PIV) or phase contrast magnetic resonance imaging (PC-MRI). In this study, we investigated pulsatile flow in an elastic, image-based, patient-specific cerebral aneurysm model using PIV. The phantom model was carefully fabricated using a specialized technique by silicone elastomer. We explored the hemodynamics of the WSS and the kinetic energy cascade (KEC) in the elastic model compared with a rigid model, at the apex of the bifurcation of the middle cerebral artery (MCA) in vitro. The effects of elasticity on the WSS, WSS gradient (WSSG), and tensile strength of the aneurysm wall were also investigated, in addition to the effect of wall elasticity on the KEC compared to a rigid wall. Although the WSSG around the stagnation point had a large positive value, there was no difference between the two models. In particular, wall elasticity suppressed the WSS magnitude around the stagnation point and attenuated the KEC (i.e., the flow fluctuation). Future studies examining KEC frequency and WSS characteristics in a phantom model should consider assessing elasticity.
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14 May 2022
Research Article|
May 10 2022
Characteristic effect of wall elasticity on flow instability and wall shear stress of a full-scale, patient-specific aneurysm model in the middle cerebral artery: An experimental approach
Ryuhei Yamaguchi
;
Ryuhei Yamaguchi
a)
1
Institute of Fluid Science, Tohoku University
980-8577, Miyagi, Japan
a)Author to whom correspondence should be addressed: yryuhei63@gmail.com; Tel.:. FAX:
+81-22-217-5224
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Gaku Tanaka;
Gaku Tanaka
b)
2
Graduate School of Engineering, Chiba University
, 263-8522, Chiba, Japan
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Nadia Shaira Shafii
;
Nadia Shaira Shafii
c)
3
Faculty of Engineering, Universiti Teknologi Malaysia
, Johor Bahru 81310, Malaysia
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Kahar Osman;
Kahar Osman
d)
3
Faculty of Engineering, Universiti Teknologi Malaysia
, Johor Bahru 81310, Malaysia
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Yasutomo Shimizu;
Yasutomo Shimizu
e)
4
Healthcare Solution Unit II, Fujitsu Japan Limited
108-0075, Tokyo, Japan
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Khalid M. Saqr
;
Khalid M. Saqr
f)
1
Institute of Fluid Science, Tohoku University
980-8577, Miyagi, Japan
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Makoto Ohta
Makoto Ohta
g)
1
Institute of Fluid Science, Tohoku University
980-8577, Miyagi, Japan
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a)Author to whom correspondence should be addressed: yryuhei63@gmail.com; Tel.:. FAX:
+81-22-217-5224
b)
Electronic mail: gtanaka@faculty.chiba-u.jp
c)
Electronic mail: nadshaira@gmail.com
d)
Electronic mail: kaharosman@utm.my
e)
Electronic mail: shimizuy@jp.fujitsu.com
f)
Electronic mail: kh.saqr@gmail.com
g)
Electronic mail: makoto.ohta@tohoku.ac.jp
J. Appl. Phys. 131, 184701 (2022)
Article history
Received:
January 16 2022
Accepted:
April 16 2022
Citation
Ryuhei Yamaguchi, Gaku Tanaka, Nadia Shaira Shafii, Kahar Osman, Yasutomo Shimizu, Khalid M. Saqr, Makoto Ohta; Characteristic effect of wall elasticity on flow instability and wall shear stress of a full-scale, patient-specific aneurysm model in the middle cerebral artery: An experimental approach. J. Appl. Phys. 14 May 2022; 131 (18): 184701. https://doi.org/10.1063/5.0085417
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