This paper presents a modified design of a high-resolution fiber optic sensor that operates on the surface plasmon resonance effect. The sensor is based on the well-known method of generating surface plasmons with the help of an inscribed tilted fiber Bragg grating that excites the cladding modes. Because the original design solution used a polarizing fiber, it was possible to significantly improve the stability of the sensor readings. The specialized mathematical apparatus was used to determine the surface plasmon resonance spectral position. It was experimentally shown that the limit of detection to the refractive index of such a sensor is 2 × 10−6 refractive index units. The sensor's response to the investigated medium temperature change is presented and analyzed. The high resolution of the sensor in detecting protein molecules was demonstrated. Such sensors open wide perspectives for their application in real high-sensitivity sensor systems as biosensors for immune analysis in medical diagnostics.

1.
J.
Homola
,
S. S.
Yee
, and
G.
Gauglitz
, “
Surface plasmon resonance sensors: Review
,”
Sens. Actuators, B
54
(
1–2
),
3
15
(
1999
).
2.
R.
Kashyap
and
G.
Nemova
, “
Surface plasmon resonance-based fiber and planar waveguide sensors
,”
J. Sens.
2009
,
645162
.
3.
E.
Klantsataya
,
P.
Jia
,
H.
Ebendorff-Heidepriem
,
T. M.
Monro
, and
A.
François
, “
Plasmonic fiber optic refractometric sensors: From conventional architectures to recent design trends
,”
Sensors
17
(
1
),
12
35
(
2017
).
4.
R. L.
Rich
and
D. G.
Myszka
, “
Survey of the year 2004 commercial optical biosensor literature
,”
J. Mol. Recognit.
18
(
6
),
431
478
(
2005
).
5.
V.
Márquez-Cruz
and
J.
Albert
, “
High resolution NIR TFBG-assisted biochemical sensors
,”
J. Lightwave Technol.
33
(
16
),
3363
3373
(
2015
).
6.
E.
Kretschmann
and
H.
Raether
, “
Radiative decay of non radiative surface plasmons excited by light
,”
Z. Naturforsch. A
23
(
12
),
2135
2136
(
1968
).
7.
A.
Otto
, “
Excitation of nonradiative surface plasma waves in silver by the method of frustrated total reflection
,”
Z. Phys.
216
,
398
410
(
1968
).
8.
C.
Caucheteur
,
T.
Guo
, and
J.
Albert
, “
Review of plasmonic fiber optic biochemical sensors: Improving the limit of detection
,”
Anal. Bioanal. Chem.
407
(
14
),
3883
3897
(
2015
).
9.
S. K.
Srivastava
and
B. D.
Gupta
, “
Fiber optic plasmonic sensors: Past, present and future
,”
Open Opt. J.
7
,
58
83
(
2013
).
10.
W.
Ni
,
H.
Chen
,
X.
Kou
,
M. H.
Yeung
, and
J.
Wang
,
J. Phys. Chem. C
112
(
22
),
8105
8109
(
2008
).
11.
Y.
Zhao
,
Z.
Deng
, and
Q.
Wang
, “
Fiber optic SPR sensor for liquid concentration measurement
,”
Sens. Actuators, B
192
,
229
233
(
2014
).
12.
Y.
Lin
, “
Characteristics of optical fiber refractive index sensor based on surface plasmon resonance
,”
Microwave Opt. Technol. Lett.
55
(
3
),
574
576
(
2013
).
13.
S. K.
Srivastava
,
R.
Verma
, and
B. D.
Gupta
, “
Surface plasmon resonance based fiber optic sensor for the detection of low water content in ethanol
,”
Sens. Actuators, B
153
(
1
),
194
198
(
2011
).
14.
W.
Qin
,
S.
Li
,
Y.
Yao
,
X.
Xin
, and
J.
Xue
, “
Analyte-filled core self-calibration microstructured optical fiber based plasmonic sensor for detecting high refractive index aqueous analyte
,”
Opt. Lasers Eng.
58
,
1
8
(
2014
).
15.
J.
Albert
,
S.
Lepinay
,
C.
Caucheteur
, and
M. C.
DeRosa
, “
High resolution grating-assisted surface plasmon resonance fiber optic aptasensor
,”
Methods
63
(
3
),
239
254
(
2013
).
16.
C.
Ribaut
,
M.
Loyez
,
J.
Larrieu
,
S.
Chevineau
,
P.
Lambert
,
M.
Remmelink
,
R.
Wattiez
, and
C.
Caucheteur
, “
Cancer biomarker sensing using packaged plasmonic optical fiber gratings: Towards in vivo diagnosis
,”
Biosens. Bioelectron.
92
,
449
456
(
2017
).
17.
Y.
Shevchenko
and
J.
Albert
, “
Plasmon resonances in gold-coated tilted fiber Bragg gratings
,”
Opt. Lett.
32
(
2
),
211
212
(
2007
).
18.
Y.
Shevchenko
,
G.
Camci-Unal
,
D. F.
Cuttica
,
M. R.
Dokmeci
,
J.
Albert
, and
A.
Khademhosseini
, “
Surface plasmon resonance fiber sensor for real-time and label-free monitoring of cellular behavior
,”
Biosens. Bioelectron.
56
,
359
367
(
2014
).
19.
J.
Albert
,
L. Y.
Shao
, and
C.
Caucheteur
, “
Tilted fiber Bragg grating sensors
,”
Laser Photonics Rev.
7
(
1
),
83
108
(
2013
).
20.
K. A.
Tomyshev
,
D. K.
Tazhetdinova
, and
O. V.
Butov
, “
High-resolution fiber plasmon sensor
,” in
Proceedings of PIERS
, St. Petersburg, Russia (
2017
), pp.
53
56
.
21.
T.
Guo
,
F.
Liu
,
X.
Liang
,
X.
Qiu
,
Y.
Huang
,
C.
Xie
, and
P.
Xu
, “
Highly sensitive detection of urinary protein variations using tilted fiber grating sensors with plasmonic nanocoatings
,”
Biosens. Bioelectron.
78
,
221
228
(
2016
).
22.
L.
Han
,
T.
Guo
,
C.
Xie
,
P.
Xu
,
J.
Lao
,
X.
Zhang
,
Y.
Huang
,
J.
Xu
,
X.
Chen
,
X.
Liang
,
W.
Mao
, and
B.
Guan
, “
Specific detection of aquaporin-2 using plasmonic tilted fiber grating sensors
,”
J. Lightwave Technol.
35
(
16
),
3360
3365
(
2017
).
23.
C.
Ribaut
,
V.
Voisin
,
V.
Malachovská
,
V.
Dubois
,
P.
Mégret
,
R.
Wattiez
, and
C.
Caucheteur
, “
Small biomolecule immunosensing with plasmonic optical fiber grating sensor
,”
Biosens. Bioelectron.
77
,
315
322
(
2016
).
24.
K. A.
Tomyshev
,
Y. K.
Chamorovskiy
,
V. E.
Ustimchik
, and
O. V.
Butov
, “
Polarization stable plasmonic sensor based on tilted fiber Bragg grating
,”
Proc. SPIE
10323
,
103235K
(
2017
).
25.
O. V.
Butov
,
K. M.
Golant
, and
K. A.
Tomyshev
, “
Recoating of fiber Bragg gratings with metals
,”
presented at 11-th International Symposium on SiO2
, Advanced Dielectrics and Related Devices, Nice, France, June
2016
.
26.
K.-Y.
Chu
and
A. R.
Thompson
, “
Densities and refractive indices of alcohol-water solutions of n-propyl, isopropyl, and methyl alcohols
,”
J. Chem. Eng. Data
7
(
3
),
358
360
(
1962
).
27.
V.
Voisin
,
C.
Caucheteur
,
P.
Mégret
, and
J.
Albert
, “
Interrogation technique for TFBG-SPR refractometers based on differential orthogonal light states
,”
Appl. Opt.
50
(
22
),
4257
4261
(
2011
).
28.
L.-Y.
Shao
,
Y.
Shevchenko
, and
J.
Albert
, “
Intrinsic temperature sensitivity of tilted fiber Bragg grating based surface plasmon resonance sensors
,”
Opt. Express
18
,
11464
11471
(
2010
).
29.
D.
Feng
,
W.
Zhou
,
X.
Qiao
, and
J.
Albert
, “
High resolution fiber optic surface plasmon resonance sensors with single-sided gold coatings
,”
Opt. Express
24
(
15
),
16456
(
2016
).
30.
A. N.
Bashkatov
and
E. A.
Genina
, “
Water refractive index in dependence on temperature and wavelength: A simple approximation
,”
Proc. SPIE
5068
,
393
395
(
2003
).
31.
P.
Bhatia
and
B. D.
Gupta
, “
Surface-plasmon-resonance-based fiber-optic refractive index sensor: Sensitivity enhancement
,”
Appl. Opt.
50
,
2032
2036
(
2011
).
32.
S. K.
Mishra
,
C.
Varshney
, and
B. D.
Gupta
, “
Sensitivity enhancement of surface plasmon resonance based fiber optic refractive index sensor using an additional layer of zinc oxide
,”
Proc. SPIE
8794
,
87941F
(
2013
).
33.
W.
Zhou
,
Y.
Zhou
, and
J.
Albert
, “
A true fiber optic refractometer
,”
Laser Photonics Rev.
11
(
1
),
1600157
(
2017
).
34.
J. C.
Riboh
,
A. J.
Haes
,
A. D.
McFarl
,
C. R.
Yonzon
, and
R. P.
Van Duyne
, “
A nanoscale optical biosensor: Real-time immunoassay in physiological buffer enabled by improved nanoparticle adhesion
,”
J. Phys. Chem. B
107
(
8
),
1772
1780
(
2003
).
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