Electroporation is being successfully used in biology, medicine, food processing, and biotechnology, and in some environmental applications. Recent applications also include in addition to classical electroporation, where cells are exposed to micro- or milliseconds long pulses, exposures to extremely short nanosecond pulses, i.e., high-frequency electroporation. Electric pulses are applied to cells in different structural configurations ranging from suspended cells to cells in tissues. Understanding electroporation of cells in tissues and other complex environments is a key to its successful use and optimization in various applications. Thus, explanation will be provided theoretically/numerically with relation to experimental observations by scaling our understanding of electroporation from the molecular level of the cell membrane up to the tissue level.
Skip Nav Destination
Tutorial: Electroporation of cells in complex materials and tissue
Article navigation
28 May 2016
Research Article|
May 23 2016
Tutorial: Electroporation of cells in complex materials and tissue
L. Rems;
L. Rems
a)
Faculty of Electrical Engineering,
University of Ljubljana
, Tržaška 25, SI-1000 Ljubljana, Slovenia
Search for other works by this author on:
D. Miklavčič
D. Miklavčič
b)
Faculty of Electrical Engineering,
University of Ljubljana
, Tržaška 25, SI-1000 Ljubljana, Slovenia
Search for other works by this author on:
a)
Present address: Department of Chemical Engineering, Delft University of Technology, 2628 BL Delft, The Netherlands.
b)
Author to whom correspondence should be addressed. Electronic mail: damijan.miklavcic@fe.uni-lj.si
J. Appl. Phys. 119, 201101 (2016)
Article history
Received:
January 25 2016
Accepted:
April 07 2016
Citation
L. Rems, D. Miklavčič; Tutorial: Electroporation of cells in complex materials and tissue. J. Appl. Phys. 28 May 2016; 119 (20): 201101. https://doi.org/10.1063/1.4949264
Download citation file:
Sign in
Don't already have an account? Register
Sign In
You could not be signed in. Please check your credentials and make sure you have an active account and try again.
Sign in via your Institution
Sign in via your InstitutionPay-Per-View Access
$40.00
Citing articles via
Related Content
A numerical analysis of multicellular environment for modeling tissue electroporation
Appl. Phys. Lett. (April 2012)
Assessing how electroporation affects the effective conductivity tensor of biological tissues
Appl. Phys. Lett. (November 2012)
Micro-/nanofluidics based cell electroporation
Biomicrofluidics (January 2013)
Modeling in conventional and supra electroporation for model cell with organelles
AIP Conference Proceedings (September 2015)
Recent electroporation-based systems for intracellular molecule delivery
Nanotechnology and Precision Engineering (July 2021)