A phenomenon of the noise-induced oscillatory multistability in glycolysis is studied. As a basic deterministic skeleton, we consider the two-dimensional Higgins model. The noise-induced generation of mixed-mode stochastic oscillations is studied in various parametric zones. Probabilistic mechanisms of the stochastic excitability of equilibria and noise-induced splitting of randomly forced cycles are analysed by the stochastic sensitivity function technique. A parametric zone of supersensitive Canard-type cycles is localized and studied in detail. It is shown that the generation of mixed-mode stochastic oscillations is accompanied by the noise-induced transitions from order to chaos.
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Research Article| March 01 2018
Sensitivity analysis of the noise-induced oscillatory multistability in Higgins model of glycolysis
Special Collection: Multistability and Tipping
Lev Ryashko; Sensitivity analysis of the noise-induced oscillatory multistability in Higgins model of glycolysis. Chaos 1 March 2018; 28 (3): 033602. https://doi.org/10.1063/1.4989982
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