One of the most common types of 3D printing technologies is inkjet printing due to its numerous advantages, including low cost, programmability, high resolution, throughput, and speed. Inkjet printers are also capable of fabricating artificial tissues with physiological characteristics similar to those of living tissues. These artificial tissues are used for disease modeling, drug discovery, drug screening, and replacements for diseased or damaged tissues. This paper reviews recent advancements in one of the most common 3D printing technologies, inkjet dispensing. We briefly consider common printing techniques, including fused deposition modeling (FDM), stereolithography (STL), and inkjet printing. We briefly discuss various steps in inkjet printing, including droplet generation, droplet ejection, interaction of droplets on substrates, drying, and solidification. We also discuss various parameters that affect the printing process, including ink properties (e.g., viscosity and surface tension), physical parameters (e.g., internal diameter of printheads), and actuation mechanisms (e.g., piezoelectric actuation and thermal actuation). Through better understanding of common 3D printing technologies and the parameters that influence the printing processes, new types of artificial tissues, disease models, and structures for drug discovery and drug screening may be prepared. This review considers future directions in inkjet printing research that are focused on enhancing the resolution, printability, and uniformity of printed structures.
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December 2020
Review Article|
November 16 2020
Physicochemical parameters that underlie inkjet printing for medical applications
Sina Azizi Machekposhti
;
Sina Azizi Machekposhti
1
Department of Biomedical Engineering, University of North Carolina/North Carolina State University
, Room 4130, 1845 Entrepreneur Drive, Raleigh, North Carolina 27695–7115, USA
2
Fiber and Polymer Science Program, North Carolina State University
, Raleigh, North Carolina 27695, USA
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Saeid Movahed;
Saeid Movahed
1
Department of Biomedical Engineering, University of North Carolina/North Carolina State University
, Room 4130, 1845 Entrepreneur Drive, Raleigh, North Carolina 27695–7115, USA
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Roger J. Narayan
Roger J. Narayan
a)
1
Department of Biomedical Engineering, University of North Carolina/North Carolina State University
, Room 4130, 1845 Entrepreneur Drive, Raleigh, North Carolina 27695–7115, USA
a)Author to whom correspondence should be addressed: [email protected]
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a)Author to whom correspondence should be addressed: [email protected]
Biophysics Rev. 1, 011301 (2020)
Article history
Received:
April 27 2020
Accepted:
October 14 2020
Connected Content
A companion article has been published:
Overview offers an inkling on 3D bioprinting
Citation
Sina Azizi Machekposhti, Saeid Movahed, Roger J. Narayan; Physicochemical parameters that underlie inkjet printing for medical applications. Biophysics Rev. 1 December 2020; 1 (1): 011301. https://doi.org/10.1063/5.0011924
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