Micromixers play an imperative role in chemical and biomedical systems. Designing compact micromixers for laminar flows owning a low Reynolds number is more challenging than flows with higher turbulence. Machine learning models can enable the optimization of the designs and capabilities of microfluidic systems by receiving input from a training library and producing algorithms that can predict the outcomes prior to the fabrication process to minimize development cost and time. Here, an educational interactive microfluidic module is developed to enable the design of compact and efficient micromixers at low Reynolds regimes for Newtonian and non-Newtonian fluids. The optimization of Newtonian fluids designs was based on a machine learning model, which was trained by simulating and calculating the mixing index of 1890 different micromixer designs. This approach utilized a combination of six design parameters and the results as an input data set to a two-layer deep neural network with 100 nodes in each hidden layer. A trained model was achieved with R2 = 0.9543 that can be used to predict the mixing index and find the optimal parameters needed to design micromixers. Non-Newtonian fluid cases were also optimized using 56700 simulated designs with eight varying input parameters, reduced to 1890 designs, and then trained using the same deep neural network used for Newtonian fluids to obtain R2 = 0.9063. The framework was subsequently used as an interactive educational module, demonstrating a well-structured integration of technology-based modules such as using artificial intelligence in the engineering curriculum, which can highly contribute to engineering education.
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July 2023
Research Article|
July 05 2023
Machine learning-augmented fluid dynamics simulations for micromixer educational module
Mehmet Tugrul Birtek
;
Mehmet Tugrul Birtek
(Data curation, Software, Writing – original draft)
1
School of Biomedical Sciences and Engineering, Koç University
, Istanbul 34450, Turkey
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M. Munzer Alseed
;
M. Munzer Alseed
(Data curation, Software, Writing – original draft)
2
Boğaziçi Institute of Biomedical Engineering, Boğaziçi University
, Istanbul 34684, Turkey
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Misagh Rezapour Sarabi
;
Misagh Rezapour Sarabi
(Visualization, Writing – original draft)
1
School of Biomedical Sciences and Engineering, Koç University
, Istanbul 34450, Turkey
3
Physical Intelligence Department, Max Planck Institute for Intelligent Systems
, Stuttgart 70569, Germany
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Abdollah Ahmadpour
;
Abdollah Ahmadpour
(Software, Writing – review & editing)
9
School of Mechanical Engineering, Koç University
, Istanbul 34450, Turkey
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Ali K. Yetisen
;
Ali K. Yetisen
(Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing)
4
Department of Chemical Engineering, Imperial College London
, London SW7 2AZ, United Kingdom
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Savas Tasoglu
Savas Tasoglu
a)
(Conceptualization, Funding acquisition, Project administration, Software, Supervision, Writing – review & editing)
2
Boğaziçi Institute of Biomedical Engineering, Boğaziçi University
, Istanbul 34684, Turkey
3
Physical Intelligence Department, Max Planck Institute for Intelligent Systems
, Stuttgart 70569, Germany
5
Koç University Translational Medicine Research Center (KUTTAM), Koç University
, Istanbul 34450, Turkey
6
Koç University Arçelik Research Center for Creative Industries (KUAR), Koç University
, Istanbul 34450, Turkey
7
Koç University Is Bank Artificial Intelligence Lab (KUIS AI Lab), Koç University
, Istanbul 34450, Turkey
8
Koç University Arçelik Research Center for Creative Industries (KUAR), Koç University
, Istanbul 34450, Turkey
9
School of Mechanical Engineering, Koç University
, Istanbul 34450, Turkey
a)Author to whom correspondence should be addressed: [email protected]
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a)Author to whom correspondence should be addressed: [email protected]
Biomicrofluidics 17, 044101 (2023)
Article history
Received:
February 13 2023
Accepted:
June 17 2023
Citation
Mehmet Tugrul Birtek, M. Munzer Alseed, Misagh Rezapour Sarabi, Abdollah Ahmadpour, Ali K. Yetisen, Savas Tasoglu; Machine learning-augmented fluid dynamics simulations for micromixer educational module. Biomicrofluidics 1 July 2023; 17 (4): 044101. https://doi.org/10.1063/5.0146375
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