We investigate the effect of biofouling in a microfluidic filtration system. The microfluidic platform consists of cylindrical microposts with a pore-spacing of 2 μm, which act as the filtration section of the device. One of our key findings is that there exists a critical pressure difference above which pronounced streamer formation is observed, which eventually leads to rapid clogging of the device with an accompanying exponential decrease in permeate flow. Moreover, when streamers do form, de-clogging of pores also occurs intermittently, which leads to small time scale fluctuations [O(101 s)] superimposed upon the large time scale [O(102 min)] clogging of the system. These de-clogging phenomena lead to a sharp increase in water permeation through the microfluidic filtration device but rates the water quality as biomass debris is transported in the permeate. Streamer-based clogging shares similarities with various fouling mechanisms typically associated with membranes. Finally, we also show that the pH of the feed strongly affects biofouling of the microfluidic filtration system.

1.
A.
Karimi
,
D.
Karig
,
A.
Kumar
, and
A. M.
Ardekani
,
Lab Chip
15
,
23
42
(
2015
).
2.
I.
Biswas
,
R.
Ghosh
,
M.
Sadrzadeh
, and
A.
Kumar
,
Sci. Rep.
6
,
32204
(
2016
).
3.
M.
Hassanpourfard
,
Z.
Nikakhtari
,
R.
Ghosh
,
S.
Das
,
T.
Thundat
,
Y.
Liu
, and
A.
Kumar
,
Sci. Rep.
5
,
13070
(
2015
).
4.
A.
Valiei
,
A.
Kumar
,
P. P.
Mukherjee
,
Y.
Liu
, and
T.
Thundat
,
Lab Chip
12
,
5133
5137
(
2012
).
5.
M.
Hassanpourfard
,
R.
Ghosh
,
T.
Thundat
, and
A.
Kumar
,
Lab Chip
16
,
4091
4096
(
2016
).
6.
K.
Drescher
,
Y.
Shen
,
B. L.
Bassler
, and
H. A.
Stone
,
Proc. Natl. Acad. Sci. U. S. A.
110
,
4345
4350
(
2013
).
7.
A.
Marty
,
C.
Roques
,
C.
Causserand
, and
P.
Bacchin
,
Biofouling
28
,
551
562
(
2012
).
8.
A.
Houari
,
J.
Picard
,
H.
Habarou
,
L.
Galas
,
H.
Vaudry
,
V.
Heim
, and
P.
Di Martino
,
Biofouling
24
,
235
240
(
2008
).
9.
M. K.
Kim
,
K.
Drescher
,
O. S.
Pak
,
B. L.
Bassler
, and
H. A.
Stone
,
New J. Phys.
16
,
065024
(
2014
).
10.
W. M.
Weaver
,
V.
Milisavljevic
,
J. F.
Miller
, and
D.
Di Carlo
,
Appl. Environ. Microbiol.
78
,
5890
5896
(
2012
).
11.
N.
Debnath
,
M.
Hassanpourfard
,
R.
Ghosh
,
J.
Trivedi
,
T.
Thundat
,
M.
Sadrzadeh
, and
A.
Kumar
,
Soft Matter
13
,
8698
8705
(
2017
).
12.
F.
Paquet-Mercier
,
M.
Parvinzadeh Gashti
,
J.
Bellavance
,
S. M.
Taghavi
, and
J.
Greener
,
Lab Chip
16
,
4710
4717
(
2016
).
13.
W.
Guo
,
H. H.
Ngo
, and
J.
Li
,
Bioresour. Technol.
122
,
27
34
(
2012
).
14.
Y. W. Y.
Miura
and
S.
Okabe
,
Environ. Sci. Technol.
41
,
632
638
(
2007
).
15.
A.
Matin
,
Z.
Khan
,
S. M. J.
Zaidi
, and
M. C.
Boyce
,
Desalination
281
,
1
16
(
2011
).
16.
P.
Bacchin
,
A.
Marty
,
P.
Duru
,
M.
Meireles
, and
P.
Aimar
,
Adv. Colloid Interface Sci.
164
,
2
11
(
2011
).
17.
A.
Marty
,
C.
Causserand
,
C.
Roques
, and
P.
Bacchin
,
Biomicrofluidics
8
,
014105
(
2014
).
18.
M.
Mulder
,
Basic Principles of Membrane Technology
(
Springer
,
1998
), Vol.
72
, p.
564
.
19.
M.
Hassanpourfard
,
X.
Sun
,
A.
Valiei
,
P.
Mukherjee
,
T.
Thundat
,
Y.
Liu
, and
A.
Kumar
,
J. Visualized Exp.
90
,
e51732
(
2014
).
20.
G.
Shao
,
J.
Wu
,
Z.
Cai
, and
W.
Wang
,
Sens. Actuators A
178
,
230
236
(
2012
).
21.
A.
Perl
,
D. N.
Reinhoudt
, and
J.
Huskens
,
Adv. Mater.
21
,
2257
2268
(
2009
).
22.
Y. C.
Kung
,
K. W.
Huang
,
Y. J.
Fan
, and
P. Y.
Chiou
,
Lab Chip
15
,
1861
1868
(
2015
).
23.
J.
Cooper McDonald
and
G. M.
Whitesides
,
Acc. Chem. Res.
35
,
491
499
(
2002
).
24.
M.
Liu
,
J.
Sun
,
Y.
Sun
,
C.
Bock
, and
Q.
Chen
,
J. Micromech. Microeng.
19
,
035028
(
2009
).
25.
M. L.
Workentine
,
S.
Wang
,
H.
Ceri
, and
R. J.
Turner
,
BMC Microbiol.
13
(
1–7
),
175
(
2013
).
26.
F. C. S.
Zuber
,
C.
Keel
,
A.
Mattart
,
C.
Blumer
,
G.
Pessi
,
C.
Gigot-Bonnefoy
,
U.
Schnider-Keel
,
S.
Heeb
,
C.
Reimmann
, and
D.
Haas
,
Mol. Plant-Microbe Interact.
16
,
634
644
(
2003
).
27.
H. L.
Lin
,
C. C.
Lin
,
Y. J.
Lin
,
H. C.
Lin
,
C. M.
Shih
,
C. R.
Chen
,
R. N.
Huang
, and
T. C.
Kuo
,
Appl. Environ. Microbiol.
76
,
1683
1685
(
2010
).
28.
M. R.
Maia
,
S.
Marques
,
A. R.
Cabrita
,
R. J.
Wallace
,
G.
Thompson
,
A. J.
Fonseca
, and
H. M.
Oliveira
,
Front. Microbiol.
7
,
1381
(
2016
).
29.
K.
Stevenson
,
A. F.
McVey
,
I. B.
Clark
,
P. S.
Swain
, and
T.
Pilizota
,
Sci. Rep.
6
,
38828
(
2016
).
30.
J. H.
van Heerden
,
H.
Kempe
,
A.
Doerr
,
T.
Maarleveld
,
N.
Nordholt
, and
F. J.
Bruggeman
,
Sci. Rep.
7
,
16094
(
2017
).
31.
S.
Babel
and
S.
Takizawa
,
Desalination
261
,
46
51
(
2010
).
32.
C. C.
Ho
and
A. L.
Zydney
,
J. Colloid Interface Sci.
232
,
389
399
(
2000
).
33.
I.
Biswas
,
R.
Ghosh
,
M.
Sadrzadeh
, and
A.
Kumar
,
J. Colloid Interface Sci.
522
,
249
255
(
2018
).
34.
M.
Hayatbakhsh
,
M.
Sadrzadeh
,
D.
Pernitsky
,
S.
Bhattacharjee
, and
J.
Hajinasiri
,
Desalin. Water Treat.
57
,
14869
14887
(
2015
).
35.
B.
Van der Bruggen
,
C.
Vandecasteele
,
T.
Van Gestel
,
W.
Doyen
, and
R.
Leysen
,
Environ. Prog.
22
,
46
56
(
2003
).
36.
S.
Das
and
A.
Kumar
,
Sci. Rep.
4
,
7126
(
2014
).
37.
Z.
Wang
,
Z.
Wu
,
X.
Yin
, and
L.
Tian
,
J. Membr. Sci.
325
,
238
244
(
2008
).
38.
Z.
He
,
D. J.
Miller
,
S.
Kasemset
,
D. R.
Paul
, and
B. D.
Freeman
,
J. Membr. Sci.
525
,
25
34
(
2017
).
39.
B.
Khorshidi
,
J.
Hajinasiri
,
G.
Ma
,
S.
Bhattacharjee
, and
M.
Sadrzadeh
,
J. Membr. Sci.
500
,
151
160
(
2016
).
40.
Lijie Zhou
,
S.
Xia
,
Z.
Zhang
,
B.
Ye
,
X.
Xu
,
Z.
Gu
, and
X.
Wang
,
J. Water Sustainability
4
,
90
100
(
2014
).
41.
S.
Xia
,
L.
Zhou
,
Z.
Zhang
, and
J.
Li
,
J. Environ. Sci.
24
,
2035
2040
(
2012
).
42.
M.
Poustia
and
J.
Greener
,
Surface Science.
676
,
56
60
(
2018
).
43.
P.
Stoodley
,
D.
Debeer
, and
H. M.
Lappin-Scott
,
Antimicrob. Agents Chemother.
41
,
1876
1879
(
1997
) PMCID: PMC164028; PMID: 9303377.
44.
I.
Dogsa
,
M.
Kriechbaum
,
D.
Stopar
, and
P.
Laggner
,
Biophys. J.
89
,
2711
2720
(
2005
).
45.
A.
Hostacka
,
I.
Čiznar
, and
M.
Štefkovicova
,
Folia Microbiol.
55
,
75
78
(
2010
).
46.
A.
Maiti
,
M.
Sadrezadeh
,
S.
Guha Thakurta
,
D. J.
Pernitsky
, and
S.
Bhattacharjee
,
Energy Fuels
26
,
5604
5612
(
2012
).
47.
J.
Hermia
,
Trans. IChemE
60
,
183
187
(
1982
).
48.
B.
Khorshidi
,
I.
Biswas
,
T.
Ghosh
,
T.
Thundat
, and
M.
Sadrzadeh
,
Sci. Rep.
8
,
784
(
2018
).
49.
B.
Khorshidi
,
T.
Thundat
,
D.
Pernitsky
, and
M.
Sadrzadeh
,
J. Membr. Sci.
535
,
248
257
(
2017
).
50.
B.
Khorshidi
,
B.
Soltannia
,
T.
Thundat
, and
M.
Sadrzadeh
,
J. Membr. Sci.
523
,
336
345
(
2017
).
51.
D. J.
Miller
,
S.
Kasemset
,
L.
Wang
,
D. R.
Paul
, and
B. D.
Freeman
,
J. Membr. Sci.
452
,
171
183
(
2014
).
52.
F.
Li
,
J.
Meng
,
J.
Ye
,
B.
Yang
,
Q.
Tian
, and
C.
Deng
,
Desalination
344
,
422
430
(
2014
).

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