Acoustofluidics has a strong pedigree in microscale manipulation, with particle and cell separation and patterning arising from acoustic pressure gradients. Acoustic waveguides are a promising candidate for localizing force fields in microfluidic devices, for which computational modelling is an important design tool. Meshed finite element analysis is a popular approach for this, yet its computation time increases rapidly when complex geometries are used, limiting its usefulness. Here, we present an analytical model of the acoustic pressure field in a microchannel arising from a surface acoustic wave (SAW) boundary condition that computes in milliseconds and provide the simulation code in the supplementary material. Unlike finite element analysis, the computation time of our model is independent of microchannel or waveguide shape, making it ideal for designing and optimising microscale waveguide structures. We provide experimental validation of our model with cases including near-field acoustic patterning of microparticles from a travelling SAW and two-dimensional patterning from a standing SAW and explore the design of waveguides for localised particle or cell capture.
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March 2018
Research Article|
March 06 2018
A rapid and meshless analytical model of acoustofluidic pressure fields for waveguide design
Richard O'Rorke
;
Richard O'Rorke
1
Pillar of Engineering Product Development, Singapore University of Technology and Design
, 8 Somapah Road, Singapore
, 487372
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David Collins
;
David Collins
1
Pillar of Engineering Product Development, Singapore University of Technology and Design
, 8 Somapah Road, Singapore
, 4873722
Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology
, Cambridge, Massachusetts 02139, USA
3
Department of Biological Engineering, Massachusetts Institute of Technology
, Cambridge, Massachusetts 02139, USA
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Ye Ai
Ye Ai
a)
1
Pillar of Engineering Product Development, Singapore University of Technology and Design
, 8 Somapah Road, Singapore
, 487372a)Author to whom correspondence should be addressed: [email protected]
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a)Author to whom correspondence should be addressed: [email protected]
Biomicrofluidics 12, 024104 (2018)
Article history
Received:
January 01 2018
Accepted:
February 23 2018
Citation
Richard O'Rorke, David Collins, Ye Ai; A rapid and meshless analytical model of acoustofluidic pressure fields for waveguide design. Biomicrofluidics 1 March 2018; 12 (2): 024104. https://doi.org/10.1063/1.5021117
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