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| October 11 2023
Development of a dual-flow tissue perfusion device for modeling the gastrointestinal tract–brain axis
Lydia Baldwin, Emily J. Jones et al.
Despite the large number of microfluidic devices that have been described over the past decade for the study of tissues and organs, few have become widely adopted. There are many reasons for this ...
| April 27 2023
Microbial stir bars: Light-activated rotation of tethered bacterial cells to enhance mixing in stagnant fluids
Jyoti P. Gurung, Moein Navvab Kashani et al.
Microfluidics devices are gaining significant interest in biomedical applications. However, in a micron-scale device, reaction speed is often limited by the slow rate of diffusion of the reagents. ...
| January 03 2023
3D collagen microchamber arrays for combined chemotherapy effect evaluation on cancer cell numbers and migration
Jingru Yao, Guoqiang Li et al.
Breast cancer metastasis involves complex mechanisms, particularly when patients are undergoing chemotherapy. In tissues, tumor cells encounter cell–cell interactions, cell–microenvironment ...
| October 27 2022
Yiming Qiao, Zixue Ma et al.
We have determined the susceptibility of T4 DNA (166 kilobase pairs, kbp) to fragmentation under steady shear in a cone-and-plate rheometer. After shearing for at least 30 min at a shear rate of ...
| October 26 2021
High-throughput deterministic pairing and coculturing of single cells in a microwell array using combined hydrodynamic and recirculation flow captures
Lei Fan, Zhangyan Guan et al.
Single-cell level coculture facilitates the study of cellular interactions for uncovering unknown physiological mechanisms, which are crucial for the development of new therapies for diseases. ...
| March 30 2021
Recent developments in microfluidic synthesis of artificial cell-like polymersomes and liposomes for functional bioreactors
Hanjin Seo, Hyomin Lee
Recent advances in droplet microfluidics have led to the fabrication of versatile vesicles with a structure that mimics the cellular membrane. These artificial cell-like vesicles including ...
| November 16 2023
Sangjin Seo, Taesung Kim
Gas-permeable membranes (GPMs) and membrane-like micro-/nanostructures offer precise control over the transport of liquids, gases, and small molecules on microchips, which has led to the possibility ...
| November 13 2023
Yukun He, Yi Qiao et al.
Droplet microfluidics is an attractive technology to run parallel experiments with high throughput and scalability while maintaining the heterogeneous features of individual samples or reactions. ...
| November 01 2023
Kuan-Ming Lai, Zhenya Liu et al.
Microfluidic chips that can sort mixtures of cells and other particles have important applications in research and healthcare. However, designing a sorter chip for a given application is a slow and ...