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| April 27 2023
Microbial stir bars: Light-activated rotation of tethered bacterial cells to enhance mixing in stagnant fluids
Jyoti P. Gurung, Moein Navvab Kashani et al.
Microfluidics devices are gaining significant interest in biomedical applications. However, in a micron-scale device, reaction speed is often limited by the slow rate of diffusion of the reagents. ...
| January 03 2023
3D collagen microchamber arrays for combined chemotherapy effect evaluation on cancer cell numbers and migration
Jingru Yao, Guoqiang Li et al.
Breast cancer metastasis involves complex mechanisms, particularly when patients are undergoing chemotherapy. In tissues, tumor cells encounter cell–cell interactions, cell–microenvironment ...
| December 05 2022
I-LIFT (image-based laser-induced forward transfer) platform for manipulating encoded microparticles
Sumin Lee, Wooseok Lee et al.
Encoded microparticles have great potential in small-volume multiplexed assays. It is important to link the micro-level assays to the macro-level by indexing and manipulating the microparticles to ...
| October 27 2022
Yiming Qiao, Zixue Ma et al.
We have determined the susceptibility of T4 DNA (166 kilobase pairs, kbp) to fragmentation under steady shear in a cone-and-plate rheometer. After shearing for at least 30 min at a shear rate of ...
| October 26 2021
High-throughput deterministic pairing and coculturing of single cells in a microwell array using combined hydrodynamic and recirculation flow captures
Lei Fan, Zhangyan Guan et al.
Single-cell level coculture facilitates the study of cellular interactions for uncovering unknown physiological mechanisms, which are crucial for the development of new therapies for diseases. ...
| March 30 2021
Recent developments in microfluidic synthesis of artificial cell-like polymersomes and liposomes for functional bioreactors
Hanjin Seo, Hyomin Lee
Recent advances in droplet microfluidics have led to the fabrication of versatile vesicles with a structure that mimics the cellular membrane. These artificial cell-like vesicles including ...
| September 18 2023
Label-free microfluidic isolation of functional and viable lymphocytes from peripheral blood mononuclear cells
Abhishek Raj, Katily Ramirez et al.
The separation of peripheral blood mononuclear cells (PBMCs) into constituent blood cell types is a vital step to obtain immune cells for autologous cell therapies. The ability to separate PBMCs ...
| September 18 2023
Leyla Akh, Diane Jung et al.
Microfluidic cell sorting has shown promising advantages over traditional bulky cell sorting equipment and has demonstrated wide-reaching applications in biological research and medical diagnostics. ...
| September 15 2023
Protein array processing software for automated semiquantitative analysis of serum antibody repertoires
Ajeet Singh Yadav, Chin Hong Ooi et al.
Effective immunotherapies activate natural antitumor immune responses in patients undergoing treatment. The ability to monitor immune activation in response to immunotherapy is critical in measuring ...