Nanofibers are microstructured materials that span a broad range of applications from tissue engineering scaffolds to polymer transistors. An efficient method of nanofiber production is rotary jet-spinning (RJS), consisting of a perforated reservoir rotating at high speeds along its axis of symmetry, which propels a liquid, polymeric jet out of the reservoir orifice that stretches, dries, and eventually solidifies to form nanoscale fibers. We report a minimal scaling framework complemented by a semi-analytic and numerical approach to characterize the regimes of nanofiber production, leading to a theoretical model for the fiber radius consistent with experimental observations. In addition to providing a mechanism for the formation of nanofibers, our study yields a phase diagram for the design of continuous nanofibers as a function of process parameters with implications for the morphological quality of fibers.
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14 November 2011
Research Article|
November 15 2011
A simple model for nanofiber formation by rotary jet-spinning
Paula Mellado;
Paula Mellado
1School of Engineering and Applied Sciences, Wyss Institute of Biologically Inspired Engineering,
Harvard University
, Cambridge, Massachusetts 02138, USA
2Kavli Institute for NanoBio Science and Technology,
Harvard University
, Cambridge, Massachusetts 02138, USA
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Holly A. McIlwee;
Holly A. McIlwee
1School of Engineering and Applied Sciences, Wyss Institute of Biologically Inspired Engineering,
Harvard University
, Cambridge, Massachusetts 02138, USA
3Disease Biophysics Group, Harvard Stem Cell Institute,
Harvard University
, Cambridge, Massachusetts 02138, USA
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Mohammad R. Badrossamay;
Mohammad R. Badrossamay
1School of Engineering and Applied Sciences, Wyss Institute of Biologically Inspired Engineering,
Harvard University
, Cambridge, Massachusetts 02138, USA
3Disease Biophysics Group, Harvard Stem Cell Institute,
Harvard University
, Cambridge, Massachusetts 02138, USA
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Josue A. Goss;
Josue A. Goss
1School of Engineering and Applied Sciences, Wyss Institute of Biologically Inspired Engineering,
Harvard University
, Cambridge, Massachusetts 02138, USA
3Disease Biophysics Group, Harvard Stem Cell Institute,
Harvard University
, Cambridge, Massachusetts 02138, USA
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L. Mahadevan;
L. Mahadevan
a)
1School of Engineering and Applied Sciences, Wyss Institute of Biologically Inspired Engineering,
Harvard University
, Cambridge, Massachusetts 02138, USA
2Kavli Institute for NanoBio Science and Technology,
Harvard University
, Cambridge, Massachusetts 02138, USA
4Department of Physics,
Harvard University
, Cambridge, Massachusetts 02138, USA
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Kevin Kit Parker
Kevin Kit Parker
a)
1School of Engineering and Applied Sciences, Wyss Institute of Biologically Inspired Engineering,
Harvard University
, Cambridge, Massachusetts 02138, USA
3Disease Biophysics Group, Harvard Stem Cell Institute,
Harvard University
, Cambridge, Massachusetts 02138, USA
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a)
Authors to whom correspondence should be addressed. Electronic addresses: kkparker@seas.harvard.edu and lm@seas.harvard.edu.
Appl. Phys. Lett. 99, 203107 (2011)
Article history
Received:
September 03 2011
Accepted:
October 20 2011
Citation
Paula Mellado, Holly A. McIlwee, Mohammad R. Badrossamay, Josue A. Goss, L. Mahadevan, Kevin Kit Parker; A simple model for nanofiber formation by rotary jet-spinning. Appl. Phys. Lett. 14 November 2011; 99 (20): 203107. https://doi.org/10.1063/1.3662015
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