Highly luminescent, stable, and biocompatible quantum dots (QDs) with no protective shells have been applied for fluorescence imaging of biological living cells. Structural and luminescent properties of the QDs are described. Marking of the living cells with such QDs highlights the penetration, accumulation, and heterogeneous distribution of the QDs inside the intracellular space.
REFERENCES
1.
A.
Miyawaki
, A.
Sawano
, and T.
Kogure
, Nat. Cell Biol.
5
, S1
(2003
).2.
A. P.
Alivisatos
, Science
271
, 933
(1996
).3.
F.
Pinaud
, X.
Michalet
, L. A.
Bentolila
, J. M.
Tsay
, S.
Doose
, J. J.
Li
, G.
Iyer
, and S.
Weiss
, Biomaterials
27
, 1679
(2006
).4.
A. M.
Derfus
, W. C. W.
Chan
, and S. N.
Bhatia
, Nano Lett.
4
, 11
(2004
).5.
A.
Hoshino
, K.
Fujioka
, T.
Oku
, M.
Suga
, Y. F.
Sasaki
, T.
Ohta
, M.
Yasuhara
, K.
Suzuki
, and K.
Yamamoto
, Nano Lett.
4
, 2163
(2004
).6.
C.
Kirchner
, T.
Liedl
, S.
Kudera
, T.
Pellegrino
, A. M.
Javier
, H. E.
Gaub
, S.
Stolzle
, N.
Fertig
, and W. J.
Parak
, Nano Lett.
5
, 331
(2005
).7.
F.
Pinaud
, D.
King
, H. P.
Moore
, and S.
Weiss
, J. Am. Chem. Soc.
126
, 6115
(2004
).8.
F.
Osaki
, T.
Kanamori
, S.
Sando
, T.
Sera
, and Y.
Aoyama
, J. Am. Chem. Soc.
126
, 6520
(2004
).9.
R.
Yakimova
, R. M.
Petoral
, Jr., G. R.
Yazdi
, C.
Vahlberg
, A. Lloyd
Spetz
, and K.
Uvdal
, J. Phys. D
40
, 6435
(2007
), and references therein.10.
H.
Song
and Z.
Zhang
, Mater. Sci. Eng., A
426
, 59
(2006
).11.
X. L.
Wu
, J. Y.
Fan
, T.
Qiu
, X.
Yang
, G. G.
Siu
, and P. K.
Chu
, Phys. Rev. Lett.
94
, 026102
(2005
).12.
J. Y.
Fan
, X.
Wu
, H.
Li
, H.
Liu
, G. G.
Siu
, and P. K.
Chu
, Appl. Phys. Lett.
88
, 041909
(2006
).13.
J. Y.
Fan
, X. L.
Wu
, and P. K.
Chu
, Prog. Mater. Sci.
8
, 983
(2006
).14.
J. Y.
Fan
, X. L.
Wu
, P. Q.
Zhao
, and P. K.
Chu
, Phys. Lett. A
360
, 336
(2006
).© 2008 American Institute of Physics.
2008
American Institute of Physics
You do not currently have access to this content.
