The electrical conductivity value of the human skull is important for biophysics research of the brain. In the present study, the human brain-to-skull conductivity ratio was estimated through in vivo experiments utilizing intracranial electrical stimulation in two epilepsy patients. A realistic geometry inhomogeneous head model including the implanted silastic grids was constructed with the aid of the finite element method, and used to estimate the conductivity ratio. Averaging over 49 sets of measurements, the mean value and standard deviation of the brain-to-skull conductivity ratio were found to be 18.7 and 2.1, respectively.
REFERENCES
1.
Y. C.
Zhang
, S. A.
Zhu
, and B.
He
, Phys. Med. Biol.
49
, 2975
(2004
).2.
Y. C.
Zhang
, L.
Ding
, W.
van Drongelen
, K.
Hecox
, D. M.
Frim
, and B.
He
, Neuroimage
31
, 1513
(2006
).3.
L. A.
Neilson
, M.
Kovalyov
, and Z. J.
Koles
, Clin. Neurophysiol.
116
, 2302
(2005
).4.
P. L.
Nunez
and R.
Srinivasan
, Electric Fields of The Brain: The Neurophysics of EEG
, 2nd ed. (Oxford University Press
, New York
, 2005
), p. 251
.5.
J.
Malmivuo
and R.
Plonsey
, Bioelectromagnetism: Principles and Aplications of Bioelectric and Biomagnetic Fields
(Oxford University Press
, New York
, 1995
), p. 141
.6.
B.
He
, Y. H.
Wang
, and D. S.
Wu
, IEEE Trans. Biomed. Eng.
46
, 1264
(1999
).7.
Y.
Lai
, W.
van Drongelen
, L.
Ding
, K.
Hecox
, V. L.
Towle
, D. M.
Frim
, and B.
He
, Clin. Neurophysiol.
116
, 456
(2005
).8.
S.
Rush
and D. A.
Driscoll
, Anesth. Analg. (Baltimore)
47
, 717
(1968
).9.
D.
Cohen
and B. N.
Cuffin
, Electroencephalogr. Clin. Neurophysiol.
56
, 38
(1983
).10.
T. F.
Oostendorp
, J.
Delbeke
, and D. F.
Stegeman
, IEEE Trans. Biomed. Eng.
47
, 1487
(2000
).© 2006 American Institute of Physics.
2006
American Institute of Physics
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