We propose a simple, reliable and cost-effective method for microfluidic sorting of microparticles using an optical potential landscape projected by a composite microlens array (MLA). The MLA enables a high power efficient approach to forming composite shape and size of the projected pattern. Sorting particles by size is demonstrated both theoretically and experimentally.
REFERENCES
1.
P. Y.
Chiou
, A. T.
Ohta
, and M. C.
Wu
, Nature (London)
436
, 370
(2005
).2.
A. Y.
Fu
, C.
Spence
, A.
Scherer
, F. H.
Arnold
, and S. R.
Quake
, Nat. Biotechnol.
17
, 1109
(1999
).3.
A.
van Qudenaarden
and S. G.
Boxer
, Science
285
, 1046
(1999
).4.
C. F.
Chou
, O.
Bakajin
, S. W. P.
Turner
, T. A. J.
Duke
, S. S.
Chan
, E. C.
Cox
, H. G.
Craighead
, and R. H.
Austin
, Proc. Natl. Acad. Sci. U.S.A.
96
, 13762
(1999
).5.
L. R.
Huang
, E. C.
Cox
, R. H.
Austin
, and J. C.
Sturm
, Science
304
, 987
(2004
).6.
P. T.
Korda
, M. B.
Taylor
, and D. G.
Grier
, Phys. Rev. Lett.
89
, 128301
(2002
).7.
M. P.
MacDonald
, G. C.
Spalding
, and K.
Dholakia
, Nature (London)
426
, 421
(2003
).8.
K.
Ladavac
, L.
Kasza
, and D. G.
Grier
, Phys. Rev. E
70
, 010901
(2004
).9.
P. J.
Rodrigo
, V. R.
Daria
, and J.
Glückstad
, Opt. Express
13
, 1384
(2005
).10.
I. R.
Perch-Nielsen
, E.
Eriksson
, M.
Goksor
, J.
Enger
, P. J.
Rodrigo
, D.
Hanstorp
, and J.
Glückstad
, Proc. SPIE
6088
, 60881H
(2006
).11.
S. J.
Hart
and A. V.
Terray
, Appl. Phys. Lett.
83
, 5316
(2003
).12.
See EPAPS Document No. E-APPLAB-89-245640 for a movie file (WMV) of MLA optical sorting. The video demonstrates microfluidic sorting by size with interconnected optical lattice in the microchamber. The mixture of particles are driven uniformly from right towards left. This document can be reached through a direct link in the online articles HTML reference section or via the EPAPS homepage (http://www.aip.org/pubservs/epaps.html).
© 2006 American Institute of Physics.
2006
American Institute of Physics
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