We have developed ultrabroadband multiplex coherent anti-Stokes Raman scattering (CARS) microspectroscopy using a coherent supercontinuum in the near-infrared region generated from a photonic crystal fiber. Owing to the ultrabroadband Stokes radiation obtained from the supercontinuum, multiple vibrational modes can be excited simultaneously in the wave-number range of more than 2500cm1. A CARS imaging of a lipid vesicle is demonstrated with a high vibrational contrast.

1.
A.
Zumbusch
,
G. R.
Holtom
, and
X. S.
Xie
,
Phys. Rev. Lett.
82
,
4142
(
1999
).
2.
M.
Hashimoto
,
T.
Araki
, and
S.
Kawata
,
Opt. Lett.
25
,
1768
(
2000
).
3.
J.-X.
Cheng
,
Y. K.
Jia
,
G.
Zheng
, and
X. S.
Xie
,
Biophys. J.
83
,
502
(
2002
).
4.
M.
Mueller
and
J. M.
Schins
,
J. Phys. Chem. B
106
,
3715
(
2002
).
5.
H. N.
Paulsen
,
K. M.
Hilligsoe
,
J.
Thogersen
,
S. R.
Keiding
, and
J. J.
Larsen
,
Opt. Lett.
28
,
1123
(
2003
).
6.
T.
Ichimura
,
N.
Hayazawa
,
M.
Hashimoto
,
Y.
Inouye
, and
S.
Kawata
,
Phys. Rev. Lett.
92
,
220801
(
2004
).
7.
J.-X.
Cheng
and
X. S.
Xie
,
J. Phys. Chem. B
108
,
827
(
2004
).
8.
E. O.
Potma
and
X. S.
Xie
,
J. Raman Spectrosc.
34
,
642
(
2003
).
9.
G. W. H.
Wurpel
,
J. M.
Schins
, and
M.
Mueller
,
J. Phys. Chem. B
108
,
3400
(
2004
).
10.
C.
Otto
,
A.
Voroshilov
,
S. G.
Kruglik
, and
J.
Greve
,
J. Raman Spectrosc.
32
,
495
(
2001
).
11.
J.-X.
Cheng
,
A.
Volkmer
,
L. D.
Book
, and
X. S.
Xie
,
J. Phys. Chem. B
106
,
8493
(
2002
).
12.
P.
Russell
,
Science
299
,
358
(
2003
).
13.
J. K.
Ranka
,
R. S.
Windeler
, and
A. J.
Stentz
,
Opt. Lett.
25
,
25
(
2000
).
14.
V.
Nagarajan
,
E.
Johnson
,
P.
Schellenberg
,
W.
Parson
, and
R.
Windeler
,
Rev. Sci. Instrum.
73
,
4145
(
2002
).
15.
A. B.
Fedotov
,
P.
Zhou
,
A. P.
Tarasevitch
,
K. V.
Dukel’skii
,
Y. N.
Kondrat’ev
,
V. S.
Shevandin
,
V. B.
Smirnov
,
D.
Von der Linde
, and
A. M.
Zheltikov
,
J. Raman Spectrosc.
33
,
888
(
2002
).
16.
H.
Kano
and
H.
Hamaguchi
,
Opt. Lett.
28
,
2360
(
2003
).
17.
S. O.
Konorov
,
A. B.
Fedotov
,
D. A.
Sidorov-Biryukov
,
V. I.
Beloglazov
,
N. B.
Skibina
,
A. V.
Shcherbakov
, and
A. M.
Zheltikov
,
J. Raman Spectrosc.
34
,
688
(
2003
).
18.
S. O.
Konorov
,
D. A.
Akimov
,
A. A.
Ivanov
,
M. V.
Alfimov
, and
A. M.
Zheltikov
,
Appl. Phys. B: Lasers Opt.
78
,
565
(
2004
).
19.
H.
Kano
and
H.
Hamaguchi
,
Appl. Phys. Lett.
85
,
4298
(
2004
).
20.
H.
Kano
and
H.
Hamaguchi
,
Appl. Phys. B: Lasers Opt.
80
,
243
(
2005
).
21.
B. N.
Toleutaev
,
T.
Tahara
, and
H.
Hamaguchi
,
Appl. Phys. B: Lasers Opt.
59
,
369
(
1994
).
22.
J.-X.
Cheng
,
A.
Volkmer
, and
X. S.
Xie
,
J. Opt. Soc. Am. B
19
,
1363
(
2002
).
23.
T. W.
Kee
and
M. T.
Cicerone
,
Opt. Lett.
29
,
2701
(
2004
).
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