A complementary metal-oxide-semiconductor-compatible method is proposed to form atomic-scale germanium (Ge) quantum dots (<10 nm) for application in single-electron devices or optical devices. The formation of Ge quantum dots is realized by the Ge atoms’ segregation and agglomeration during thermal oxidation of Si1−xGex alloys. The size and distribution of the Ge dots are determined by conditions of thermal oxidation process and Ge content in the alloys. An average Ge-dot size of 5.1 nm with standard deviation of 1.79 nm and a comparatively uniform spatial distribution (dot density of 7.9×1011cm−2) could be obtained by selective oxidation of Si0.85Ge0.15/Si-on-insulator structure.

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