The synaptic response of ZnO/HfZrO memristor devices to electrical stimuli was studied. It was found that the frequency of the stimuli affects the rate of current increase, which can be explained by the cluster state of oxygen vacancies at the interface of ZnO/HfZrO. This variation in the synaptic response due to stimulus frequency was consistent with the dynamic adjustment of tolerance thresholds observed in the human brain's response to environmental stimuli. The rate of change in current, representing the sensitivity to stimuli, mirrors the biological nervous system's reaction to environmental changes, such as Ebbinghaus forgetting behavior. Additionally, frequent irregular changes in stimuli lead to a reduced lifespan of the devices, highly resembling the biological lifetime-injure on frequent environmental fluctuations. These findings highlight the memristors' significant similarity to biological nerves in response to stimuli, confirming their tremendous potential in bionic synaptic simulation applications.

1.
Q.
Wan
,
M. T.
Sharbati
,
J. R.
Erickson
,
Y.
Du
, and
F.
Xiong
, “
Emerging artificial synaptic devices for neuromorphic computing
,”
Adv. Mater. Technol.
4
(
4
),
1900037
(
2019
).
2.
S.
Yan
,
J.
Zang
,
P.
Xu
et al, “
Recent progress in ferroelectric synapses and their applications
,”
Sci. China Mater.
66
(
3
),
877
894
(
2023
).
3.
K.
Sun
,
J.
Chen
, and
X.
Yan
, “
The future of memristors: Materials engineering and neural networks
,”
Adv. Funct. Mater
31
(
8
),
2006773
(
2021
).
4.
Z.
Shen
,
C.
Zhao
,
Y.
Qi
et al, “
Advances of RRAM devices: Resistive switching mechanisms, materials and bionic synaptic application
,”
Nanomaterials
10
(
8
),
1437
(
2020
).
5.
C.
Wolf
and
D. E. J.
Linden
, “
Biological pathways to adaptability–interactions between genome, epigenome, nervous system and environment for adaptive behavior
,”
Genes, Brain Behav.
11
(
1
),
3
28
(
2012
).
6.
R. J.
Ellis
and
J. F.
Thayer
, “
Music and autonomic nervous system (dys) function
,”
Music Percept.
27
(
4
),
317
326
(
2010
).
7.
W.
Jiang
and
D.
Sun
, “
Music signal recognition based on the mathematical and physical equation inversion method
,”
Adv. Math. Phys.
2021
(
1
),
3148747
.
8.
M.
Cencini
,
M.
Falcioni
,
E.
Olbrich
,
H.
Kantz
, and
A.
Vulpiani
, “
Chaos or noise: Difficulties of a distinction
,”
Phys. Rev. E
62
(
1
),
427
(
2000
).
9.
A.
Thomas
, “
Memristor-based neural networks
,”
J. Phys. D
46
(
9
),
093001
(
2013
).
10.
Y. G.
Song
,
J. M.
Suh
,
J. Y.
Park
et al, “
Artificial adaptive and maladaptive sensory receptors based on a surface‐dominated diffusive memristor
,”
Adv. Sci.
9
(
4
),
2103484
(
2022
).
11.
Y.
Kim
,
Y. J.
Kwon
,
D. E.
Kwon
et al, “
Nociceptive memristor
,”
Adv. Mater
30
(
8
),
1704320
(
2018
).
12.
I.
Adawi
, “
Theory of the surface photoelectric effect for one and two photons
,”
Phys. Rev.
134
,
A788
(
1964
).
13.
E.
Scorza
,
U.
Birkenheuer
, and
C.
Pisani
, “
The oxygen vacancy at the surface and in bulk MgO: An embedded-cluster study
,”
J. Chem. Phys.
107
(
22
),
9645
9658
(
1997
).
14.
B.
Lee
,
K. M.
Choi
,
H.-S.
Ahn
,
S.
Han
, and
J.
Lee
, “
Oxygen vacancy clustering and electron localization in oxygen-deficient SrTiO3: LDA + U study
,”
Phys. Rev. Lett.
98
(
11
),
115503
(
2007
).
15.
R.
Jiang
,
X.
Du
,
Z.
Han
, and
W.
Sun
, “
Investigation of chemical distribution in the oxide bulk layer in Ti/HfO2/Pt memory devices using x-ray photoelectron spectroscopy
,”
Appl. Phys. Lett.
106
(
17
),
173509
(
2015
).
16.
X.
Yan
,
J.
Zhao
,
S.
Liu
et al, “
Memristor with Ag‐cluster‐doped TiO2 films as artificial synapse for neuroinspired computing
,”
Adv. Funct. Mater.
28
(
1
),
1705320
(
2018
).
17.
Z.
Wang
,
S.
Joshi
,
S. E.
Savel'ev
et al, “
Memristors with diffusive dynamics as synaptic emulators for neuromorphic computing
,”
Nat. Mater.
16
(
1
),
101
108
(
2017
).
18.
Y.
Yang
,
P.
Gao
,
S.
Gaba
,
T.
Chang
,
X.
Pan
, and
W.
Lu
, “
Observation of conducting filament growth in nanoscale resistive memories
,”
Nat. Commun.
3
(
1
),
732
(
2012
).
19.
K.
Ye
,
K.
Li
,
Y.
Lu
et al, “
An overview of advanced methods for the characterization of oxygen vacancies in materials
,”
TrAC Trends Anal. Chem
116
,
102
108
(
2019
).
20.
P. A.
Parsons
, “
Environments and evolution: Interactions between stress, resource inadequacy and energetic efficiency
,”
Biol. Rev.
80
(
4
),
589
610
(
2005
).
21.
S.
Hu
,
Y.
Liu
,
T.
Chen
et al, “
Emulating the paired-pulse facilitation of a biological synapse with a NiOx-based memristor
,”
Appl. Phys. Lett.
102
(
18
),
183510
(
2013
).
22.
T.
Reichenbach
and
A.
Hudspeth
, “
The physics of hearing: Fluid mechanics and the active process of the inner ear
,”
Rep. Prog. Phys.
77
(
7
),
076601
(
2014
).
23.
T.
Gu
, “
Metallic filament formation by aligned oxygen vacancies in ZnO-based resistive switches
,”
J. Appl. Phys.
115
(
20
),
203707
(
2014
).
24.
G.
Milano
,
M.
Aono
,
L.
Boarino
et al, “
Quantum conductance in memristive devices: Fundamentals, developments, and applications
,”
Adv. Mater.
34
(
32
),
2201248
(
2022
).
25.
F.
Kousar
,
U.
Rasheed
,
R. A.
Khalil
et al, “
First principles investigation of oxygen vacancies filaments in polymorphic Titania and their role in memristor's applications
,”
Chaos, Solitons Fractals
148
,
111024
(
2021
).
26.
S.
Hu
,
Y.
Liu
,
T.
Chen
et al, “
Emulating the Ebbinghaus forgetting curve of the human brain with a NiO-based memristor
,”
Appl. Phys. Lett.
103
(
13
),
133701
(
2013
).
27.
N. A.
Marlin
and
R. R.
Miller
, “
Associations to contextual stimuli as a determinant of long-term habituation
,”
J. Exp. Psychol.
7
(
4
),
313
(
1981
).
28.
Q.
Wan
,
F.
Zeng
,
J.
Yin
et al, “
Phase-change nanoclusters embedded in a memristor for simulating synaptic learning
,”
Nanoscale
11
(
12
),
5684
5692
(
2019
).
29.
G.
Zhuang
,
Y.
Chen
,
Z.
Zhuang
,
Y.
Yu
, and
J.
Yu
, “
Oxygen vacancies in metal oxides: Recent progress towards advanced catalyst design
,”
Sci. China Mater.
63
(
11
),
2089
2118
(
2020
).
30.
X.
Li
,
J.
Yu
,
J.
Jia
et al, “
Confined distribution of platinum clusters on MoO2 hexagonal nanosheets with oxygen vacancies as a high-efficiency electrocatalyst for hydrogen evolution reaction
,”
Nano Energy
62
,
127
135
(
2019
).
31.
Y.
Huang
,
Y.
Yu
,
Y.
Yu
, and
B.
Zhang
, “
Oxygen vacancy engineering in photocatalysis
,”
Sol. RRL
4
(
8
),
2000037
(
2020
).
32.
D.
Furman
,
J.
Campisi
,
E.
Verdin
et al, “
Chronic inflammation in the etiology of disease across the life span
,”
Nat. Med.
25
(
12
),
1822
1832
(
2019
).
33.
B.
Cetin
and
D.
Li
, “
Effect of Joule heating on electrokinetic transport
,”
Electrophoresis
29
(
5
),
994
1005
(
2008
).
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