We present a method for noninvasively imaging the hand joints using a three-dimensional (3D) photoacoustic imaging (PAI) system. This 3D PAI system utilizes cylindrical scanning in data collection and virtual-detector concept in image reconstruction. The maximum lateral and axial resolutions of the PAI system are 70 μm and 240 μm. The cross-sectional photoacoustic images of a healthy joint clearly exhibited major internal structures including phalanx and tendons, which are not available from the current photoacoustic imaging methods. The in vivo PAI results obtained are comparable with the corresponding 3.0 T MRI images of the finger joint. This study suggests that the proposed method has the potential to be used in early detection of joint diseases such as osteoarthritis.
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High resolution three-dimensional photoacoustic imaging of human finger joints in vivo
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10 August 2015
Research Article|
August 11 2015
High resolution three-dimensional photoacoustic imaging of human finger joints in vivo
Lei Xi;
Lei Xi
a)
1School of Physical Electronics,
University of Electronic Science and Technology of China
, Chengdu, Sichuan, China
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Huabei Jiang
Huabei Jiang
a)
1School of Physical Electronics,
University of Electronic Science and Technology of China
, Chengdu, Sichuan, China
2Department of Biomedical Engineering,
University of Florida
, Gainesville, Florida 32611, USA
Search for other works by this author on:
a)
Author to whom correspondence should be addressed. Electronic addresses: [email protected] and [email protected]
Appl. Phys. Lett. 107, 063701 (2015)
Article history
Received:
May 10 2015
Accepted:
July 03 2015
Citation
Lei Xi, Huabei Jiang; High resolution three-dimensional photoacoustic imaging of human finger joints in vivo. Appl. Phys. Lett. 10 August 2015; 107 (6): 063701. https://doi.org/10.1063/1.4926859
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