Engineering of gadofluoroprobes: Broad-spectrum applications from cancer diagnosis to therapy

The engineering of the Gadolinium based nanostructures have been demonstrated in this paper. Nanostructures of α-Gd₂S₃ exhibit a unique transition between ferromagnetic state and paramagnetic state of the system. It was demonstrated that their properties could be tuned for a wide range of applications ranging from hyperthermia to Magnetic Resonance Imaging, owing to their magnetic moments and large relaxivities. Metallic Gd nanoparticles obtained by reduction method were employed for cancer imaging in mice. The Gd nanoparticles were coated with Curcumin and their biomedical implications in the field of simultaneous diagnosis and therapy of cancer and related diseases has been discussed.