We report the fabrication of silica dielectrics obtained by in vitro biomineralization of recombinant silicatein. We exploit pressure-driven microfluidics to deposit silicatein which catalyses the deposition of silica features with thickness in the range 2–6 μm. We follow the biomineralization process with staining and confocal fluorescence for an incubation time up to 5 days and correspondingly characterize the leakage current through the resulting biomineralized silica layer by embedding it into a metal-insulator-metal device. We further characterize the morphology of the biosilica surface through atomic force and scanning electron microscopy and demonstrate the electrical insulation within planar electrodes patterned over such surface with leakage currents in the pA range for applied bias up to tens of V.

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