APL Bioengineering is an open access journal publishing articles specific to the understanding and advancement of physics and engineering of biological systems. The journal serves the bioengineering and biomedical research communities by publishing original research articles, reviews, and perspectives.
Fibroblasts play essential roles in cancer progression, exhibiting activation states that can either promote or inhibit tumor growth. Understanding these differential activation states is critical ...
Cardiac adaptation to hypoxic injury is regulated by dynamic interactions between cardiomyocytes and macrophages, yet the impacts of immune phenotypes on cardiac structure and contractility remain ...
Metronomic photodynamic therapy (mPDT) is a method of continuously delivering low-intensity light to a cancer lesion. This approach does not require high-intensity light, enabling the miniaturization ...
The rare, accelerated aging disease Hutchinson-Gilford Progeria Syndrome (HGPS) is commonly caused by a de novo c.1824 C > T point mutation of the LMNA gene that results in the protein progerin. ...
Thrombosis is a biological response closely related to intracranial aneurysms, and the formation of thrombi inside the aneurysm is an important determinant of outcome after endovascular therapy. As ...
Somatic activating mutations in PIK3CA are common drivers of vascular and lymphatic malformations. Despite common biophysical signatures of tissues susceptible to lesion formation, including ...
Fibroblasts play essential roles in cancer progression, exhibiting activation states that can either promote or inhibit tumor growth. Understanding these differential activation states is critical ...
The interaction between keratinocytes (KCs) and immune cells is essential in the pathogenesis of psoriasis. Understanding this crosstalk is crucial for developing effective treatment strategies. ...
Cardiac adaptation to hypoxic injury is regulated by dynamic interactions between cardiomyocytes and macrophages, yet the impacts of immune phenotypes on cardiac structure and contractility remain ...
