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APL Bioengineering is an open access journal publishing articles specific to the understanding and advancement of physics and engineering of biological systems. The journal serves the bioengineering and biomedical research communities by publishing original research articles, reviews, and perspectives.
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Research Article
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May 15 2025
Minwoo Kang, Chanhong Min et al.
Fibroblasts play essential roles in cancer progression, exhibiting activation states that can either promote or inhibit tumor growth. Understanding these differential activation states is critical ...
Research Article
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May 01 2025
Andrew A. Schmidt, Li-Mor David et al.
Cardiac adaptation to hypoxic injury is regulated by dynamic interactions between cardiomyocytes and macrophages, yet the impacts of immune phenotypes on cardiac structure and contractility remain ...
Research Article
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April 30 2025
Yujiro Itazaki, Kei Sakanoue et al.
Metronomic photodynamic therapy (mPDT) is a method of continuously delivering low-intensity light to a cancer lesion. This approach does not require high-intensity light, enabling the miniaturization ...
Editor's Picks
Research Article
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February 26 2025
Nadia O. Abutaleb, Xin D. Gao et al.
The rare, accelerated aging disease Hutchinson-Gilford Progeria Syndrome (HGPS) is commonly caused by a de novo c.1824 C > T point mutation of the LMNA gene that results in the protein progerin. ...
Research Article
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February 11 2025
Qiongyao Liu, Toni Lassila et al.
Thrombosis is a biological response closely related to intracranial aneurysms, and the formation of thrombi inside the aneurysm is an important determinant of outcome after endovascular therapy. As ...
Research Article
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February 05 2025
Wen Yih Aw, Aanya Sawhney et al.
Somatic activating mutations in PIK3CA are common drivers of vascular and lymphatic malformations. Despite common biophysical signatures of tissues susceptible to lesion formation, including ...
Most Recent
Research Article
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May 15 2025
Minwoo Kang, Chanhong Min et al.
Fibroblasts play essential roles in cancer progression, exhibiting activation states that can either promote or inhibit tumor growth. Understanding these differential activation states is critical ...
Research Article
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May 09 2025
Shun Guo, Qian Zhang et al.
The interaction between keratinocytes (KCs) and immune cells is essential in the pathogenesis of psoriasis. Understanding this crosstalk is crucial for developing effective treatment strategies. ...
Research Article
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May 01 2025
Andrew A. Schmidt, Li-Mor David et al.
Cardiac adaptation to hypoxic injury is regulated by dynamic interactions between cardiomyocytes and macrophages, yet the impacts of immune phenotypes on cardiac structure and contractility remain ...
Mechanomemory after short episodes of intermittent stresses induces YAP translocation via increasing F-actin
Fazlur Rashid, Elvis Njoki, et al.
Interstitial fluid flow in an engineered human lymph node stroma model modulates T cell egress and stromal change
Jennifer H. Hammel, Abhinav Arneja, et al.
Metronomic photodynamic therapy for deep organ cancer by implantable wireless OLEDs
Yujiro Itazaki, Kei Sakanoue, et al.