Production and Extraction of [¹⁰C]‐CO₂ From Proton Bombardment of Molten ¹⁰B₂O₃

This work describes the production of ¹⁰C $(t12 = 19 s)$ from an enriched ¹⁰B₂O₃ target using a CTI RDS‐112 11 MeV proton cyclotron. Proton beam heating is used to raise the target to a molten state (∼ 1300 °C), enabling the activity to diffuse to the surface of the melt. An infrared thermocouple monitors the melt temperature. Helium sweep gas then transports the activity to flow‐through chemistry processing for human inhalation of ¹⁰CO₂ for blood flow imaging with Positron Emission Tomography. The temperature‐related diffusion of activity out of the white‐hot molten glass target is discussed.