Synthesis and characterization of nanoparticle magnetite for biomedical application Free

Nanoparticles (NP) have been studied because of their unique physical and chemical properties compared with their bulk counterparts. The ferrite colloids, magnetite (Fe₃O₄) are the main representatives of the magnetic nanoparticles (MNPs). These ferrite colloids are characterized by a spinel crystal structure with oxygen ions forming a close-packed cubic lattice and iron ions located at the interstices. Fe₃O₄ has been attracting in biomedical applications due to their biocompatibility and their biodegradability. In this research, Fe₃O₄ nanoparticles has been successfully synthetized by using coprecipitation method by using Natrium hydroxide (NaOH) as precipitant agent, Ferrous Chloride Tetrahydrate (FeCl₂.4H₂O) and Ferric Chloride Anhydrous (FeCl₃.6H₂O) were used as precursor. Fe₃O₄ were characterized with X-Ray Diffraction (XRD), Vibrating Sample Magnetometer (VSM), and Particle Size Analysis (PSA). The results of synthesized Fe₃O₄ shown that the crystallite size 7.664 nm and the XRD pattern was match with the reference magnetite Fe₃O₄ pattern (JCPDS card number 19-0629). From PSA measurement, it shown that the average particles size was 228.9 nm with Polidispersity Index (PdI) 0.402 and the magnetic saturation value 80 emu/gram.