Effect of extraction solvent on total phenol, total flavonoid content and antioxidant activities of extract plants Punica granatum, Vitis vinifera L, Ficus carica L. and Olea europea

Several plants have high antioxidant compounds. Antioxidant compounds in plants include phenol compound and flavonoids. Plants are extracted with solvents, and different types of ingredients will show different active compounds. The combination of several plant extracts shows a higher compound content compared to a single compound. This study aims to examine the total phenol content, total flavonoids, and antioxidant activity in the combination of P. granantum, V. vitifera, F. carica and O. europea extract. The maceration method used is maceration of dry simplicia with methanol 95% solvent, fresh maceration with 95% methanol and dry simplicia with 95% ethanol solvent. Each extract measure of total phenol content and total flavonoid content and antioxidant activity using the DPPH method. The result of the antioxidant test showed the fresh maceration 95% methanol showed highest results with IC50 25.22 with a potent antioxidant activity category, total phenol content 68.43 mg/g, total flavonoid content 295.95 mg/g.