To observe the efficacy and adverse reactions of the Qingnao tablet in treatment of headache after brain concussion. Four hundred and fifty cases with headache after brain concussion were randomly divided into a treatment group (the treatment one takes Qingnao tablet 3 pills per time, 3 times per day) and two control groups (the control one takes painkiller 3 pills per time, 3 times per day. The control two takes Naoluotong pellet one bag per time, 3 times per day.) 150 cases in each group. The treatment took 10 days as a treatment course for both groups, successively for 2 treatment courses with 3-days interval between the two courses. Avoiding cold food or spicy food during the treatment courses. The results of the treatment were observed. There was no significant differences between groups in total effective reaction rate (P > 0.05). The two groups were comparable. The Qingnao tablet has the advantages of highly effective and less adverse effects in treatment.

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