The purpose of this paper is to examine energy efficiency through the study of performance in vapour compression cycle for auditorium in University of Indonesia using natural refrigerant R290. The installation of the chiller system which is the first in Indonesia within academic institution is particularly relevant in light of the gaining interest and research regarding the implementation of refrigeration system utilizing relatively low ODP and GWP refrigerant as alternative to replace the refrigerant HCFC-22. It is found that the highest COP during 64% partial cooling load is 4.27 at temperature water inlet is 8.9°C. The maximum COP during 75% partial load is 5.25 at temperature water inlet is 6,8 °C. The cooling capacity are 125.93 kW and 148.39 kW during 64% and 75% load, respectively.

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