This paper investigated the determination of amygdalin content in Keke Pian by high performance capillary electrophoresis (HPCE) method. The borax solution of 20 mmol concentration containing 15% methanol was chosen as buffer solution. The experiment was performed at a constant voltage of 18kV and UV detection wavelength of 210 nm. The content of amygdalin in Keke Pian was 11.351 mg/g (RSD=4.1%) (n=6). The recovery was in the range of 88.0% - 115.9% (n=6). This method is suitable for the detection of the content of amygdalin in Keke Pian.

Topics
Electrophoresis, Liquid chromatography, Buffer solutions
1.
Zhu
 
Yueyue
,
Fu
 
Jing
,
Nie
 
Shiming
,
Content Determination of Amygdalin in Loquat Cough Syrup by HPLC
,
Journal of Mathematical Medicine
,
28
(
11
),
1672
–
1674
(
2015
).
Google Scholar
 
2.
Zhu
 
Ri-ran
,
Simultaneous determination of five components in Chaiyin Oral Liquid by HPLC
,
Journal of Pharmaceutical Research
,
34
(
9
),
509
–
511
(
2015
).
Google Scholar
 
3.
Liu
 
Xiao-feng
,
Simultaneous determination of amygdalin, honokiol, magnolol, hesperidin and nobiletin in dingchuanzhike syrups by HPLC
,
Practical Pharmacy And Clinical Remedies
,
19
(
2
),
219
–
222
(
2016
).
Google Scholar
 
4.
Fang
 
Liqin
,
Simultaneous content determination of dan phenol, aeoniflorin and peach kernel in Guizhifuling capsule by HPLC method
,
Journal of North Pharmacy
,
12
(
5
),
5
–
6
(
2015
).
Google Scholar
 
5.
Liu
 
Junhong
,
Zhang
 
Shukun
,
Li
 
Dihua
,
Lu
 
Yuanshan
,
Simultaneous content determination of 8 components in modified Xiaochaihu Decoction simultaneously by using HPLC
,
Chinese Journal of traditional Chinese Medicine
,
31
(
3
),
979
–
981
(
2016
).
Google Scholar
 
6.
Xu
 
Guijun
,
Qi
 
Wei
,
Wang
 
Xuesong
,
Zhao
 
Min
,
Li
 
Zhijun
,
Wang
 
Youpeng
,
Simultaneous Determination of Ephedrine Hydrochloride and Amygdalin in Kangzhi Syrup by HPLC
,
China Pharmacist
,
21
(
3
),
499
–
501
(
2018
).
Google Scholar
 
7.
Jiang
 
Li
,
Li
 
Hui-lan
,
Zhang
 
Qi-yun
,
Rao
 
Yi
,
Wang
 
Yue-sheng
,
Xu
 
Guo-liang
,
Simultaneous determination of 5 components in Maxing Shigan Decoction with HPLC method
,
Chinese Journal of traditional Chinese Medicine
,
30
(
2
),
537
–
540
(
2015
).
Google Scholar
 
8.
Zhang
 
Jian-chun
,
Gou
 
Ya-jun
,
Deng
 
Yong-qiang
,
Simultaneous determination of seven effective constituents in Qiguanyan Granules by HPLC
,
Chinese Traditional Patent Medicine
,
38
(
4
),
806
–
809
(
2016
).
Google Scholar
 
9.
Xue
 
Ping
,
Li
 
Li
,
Determination of Four Ingredients in Qingfei Huatan Oral Solution by HPLC
,
Strait Pharmaceutical Journal
,
29
(
8
),
50
–
51
(
2017
).
Google Scholar
 
10.
Zhou
 
Min
,
Simultaneous determination of seven constituents in Sanfeng Ningsou Syrup by HPLC
,
Chinese Traditional Patent Medicine
,
39
(
11
),
2301
–
2304
(
2017
).
Google Scholar
 
11.
Zhu
 
Zebing
,
Zhang
 
Dewei
,
Mou
 
Lamei
,
Guo
 
Ya
,
Simultaneous Determination of Six Components in Xiao’er Kechuanling Granule by HPLC
,
China Pharmacist
,
21
(
2
),
354
–
357
(
2018
).
Google Scholar
 
12.
Tan
 
Xiong-si
,
Pang
 
Wu-yao
,
Simultaneous determination of six main constituents in Jinsangsanjie capsules by HPLC gradient elution
,
Chinese Journal of Drug Application and Monitoring
,
14
(
5
),
263
–
266
(
2017
).
Google Scholar
 
13.
Chen
 
Weifei
,
Li
 
Yuanzhen
,
Zhu
 
Xi
,
Wang
 
Ling
,
Yin
 
Hua
,
Simultaneous Determination of Pinoresinol Diglucoside, Amygdalin and Cinnamylaldehyde in Bushen Huoxue Granule
,
Chin J Mod Appl Pharm
,
32
(
4
),
463
–
466
(
2015
).
Google Scholar
 
This content is only available via PDF.
© 2019 Author(s).
2019
Author(s)